Background: The impairment of neural circuits controlling cognitive processes has been
implicated in the pathophysiology of Alzheimer's disease and related disorders (ADRD) …

Background: Social isolation (SI) and loneliness are major adult and adolescent health
concerns, particularly in the coronavirus disease 2019 (COVID-19) era. Recent prospective …

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a
social stress behavioral response. Recent studies have shown that brain-derived …

As the coronavirus disease (COVID-19) spread, local governments in China adopted severe
lockdown measures to control the pandemic. People were restricted from traveling for …

Background Opioid use disorder (OUD) is a chronic relapsing psychiatric disorder with an
enormous socioeconomic burden. Opioid overdose deaths have reached an epidemic level …

Social isolation is a potent form of psychosocial stress and is a growing public health
concern, particularly among older adults. Even prior to the onset of the COVID-19 pandemic …

Social isolation is a potent form of psychosocial stress and is a growing public health
concern, particularly among older adults. Even prior to the onset of the COVID-19 pandemic …

Mental health in the elderly is an escalating social problem as the world population ages
rapidly. Older adults are more susceptible to stressors like social isolation, which is a …

Autism spectrum disorders (ASDs) are neurodevelopmental disorders with two main
symptoms–alterations in social behaviour and communication and in repetitive behaviours …

Early postnatal development is a critical period for the configuration of neural networks that
support emotional and socio-affective behaviors. In this sense, children raised in stressful …