Transplanting neural progenitor cells to restore connectivity after spinal cord injury
Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …
individuals and society. The goal of research in this field is to find a means of restoring lost …
Polymer scaffolds facilitate spinal cord injury repair
Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …
Regenerative rehabilitation with conductive biomaterials for spinal cord injury
The individual approaches of regenerative medicine efforts alone and rehabilitation efforts
alone have not yet fully restored function after severe spinal cord injury (SCI). Regenerative …
alone have not yet fully restored function after severe spinal cord injury (SCI). Regenerative …
[HTML][HTML] Filling the gap: neural stem cells as a promising therapy for spinal cord injury
Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …
Defined alginate hydrogels support spinal cord organoid derivation, maturation, and modeling of spinal cord diseases
In the process of generating organoids, basement membrane extracts or Matrigel are often
used to encapsulate cells but they are poorly defined and contribute to reproducibility …
used to encapsulate cells but they are poorly defined and contribute to reproducibility …
[HTML][HTML] Advances in tissue engineering and innovative fabrication techniques for 3-D-structures: translational applications in neurodegenerative diseases
F Rey, B Barzaghini, A Nardini, M Bordoni, GV Zuccotti… - Cells, 2020 - mdpi.com
In the field of regenerative medicine applied to neurodegenerative diseases, one of the most
important challenges is the obtainment of innovative scaffolds aimed at improving the …
important challenges is the obtainment of innovative scaffolds aimed at improving the …
Recent advances in the regenerative approaches for traumatic spinal cord injury: materials perspective
WA Abbas, ME Ibrahim, M El-Naggar… - ACS Biomaterials …, 2020 - ACS Publications
Spinal cord injury (SCI) is a devastating health condition that may lead to permanent
disabilities and death. Understanding the pathophysiological perspectives of traumatic SCI …
disabilities and death. Understanding the pathophysiological perspectives of traumatic SCI …
[HTML][HTML] CNS organoid surpasses cell-laden microgel assembly to promote spinal cord injury repair
Z Wang, H Zhao, X Tang, T Meng, D Khutsishvili, B Xu… - Research, 2022 - spj.science.org
The choice of therapeutic agents remains an unsolved issue in the repair of spinal cord
injury. In this work, various agents and configurations were investigated and compared for …
injury. In this work, various agents and configurations were investigated and compared for …
[HTML][HTML] Current concepts of neural stem/progenitor cell therapy for chronic spinal cord injury
Chronic spinal cord injury (SCI) is a devastating condition that results in major neurological
deficits and social burden. It continues to be managed symptomatically, and no real …
deficits and social burden. It continues to be managed symptomatically, and no real …
[HTML][HTML] The role of graphene oxide nanocarriers in treating gliomas
B Wang, H Guo, H Xu, Y Chen, G Zhao, H Yu - Frontiers in oncology, 2022 - frontiersin.org
Gliomas are the most common primary malignant tumors of the central nervous system, and
their conventional treatment involves maximal safe surgical resection combined with …
their conventional treatment involves maximal safe surgical resection combined with …