High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

Gastrointestinal complaints are often reported during ascents to high altitude (> 2,500 m),
though their etiology is not known. One potential explanation is injury to the intestinal barrier …

Introduction Acetazolamide (AZM) is used for various conditions (eg, altitude sickness, sleep
apnoea, glaucoma), but therapy is often limited by its side effect profile. Our objective was to …

Rhodiola is an ancient wild plant that grows in rock areas in high-altitude mountains with a
widespread habitat in Asia, Europe, and America. From empirical belief to research studies …

In high altitudes, usually above 2500 m, travelers are faced with decreased partial pressure
of oxygen along with decreased barometric pressure. High-altitude illness, a syndrome of …

Background Acute high altitude illness is defined as a group of cerebral and pulmonary
syndromes that can occur during travel to high altitudes. It is more common above 2500 …

Background We evaluated the efficacy of acetazolamide in preventing adverse altitude
effects in patients with moderate to severe chronic obstructive pulmonary disease (COPD) …

Inflammation and vascular smooth muscle cell (VSMC) phenotypic switching are causally
linked to pulmonary arterial hypertension (PAH) pathogenesis. Carbonic anhydrase …

Whole blood carbonic anhydrase activity (CAa) is increased in patients with obstructive
sleep apnea (OSA). Our study investigated the influence of positive airway pressure (PAP) …

Background We aimed to determine whether and how the combination of acetazolamide
and remote ischemic preconditioning (RIPC) reduced the incidence and severity of acute …