Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Harnessing the Power of Gold: Advancements in Anticancer Gold Complexes and functionalized Nanoparticles

MA Malik, AA Hashmi, AS Al-Bogami… - Journal of Materials …, 2024 - pubs.rsc.org
Cancer poses a formidable challenge, necessitating improved treatment strategies. Metal-
based drugs and nanotechnology offer new hope in this battle. Versatile gold complexes …

Applications of Biodegradable Polymers in the Encapsulation of Anticancer Metal Complexes

M Redrado, Z Xiao, K Upitak, BT Doan… - Advanced Functional …, 2024 - Wiley Online Library
Metal complexes have recently attracted a lot of attention, particularly as anticancer and
antibacterial agents, owing to their versatile mechanisms and easily tunable characteristics …

Naphthoyl benzhydrazine–decorated binuclear arene Ru (ii) complexes as anticancer agents targeting human breast cancer cells

A Abirami, U Devan, R Ramesh, AAJ Velanganni… - Dalton …, 2023 - pubs.rsc.org
Breast cancer is the most dangerous type in women and its fatality rate has increased over
the past decade. To develop more potent and target-specific breast cancer drugs, six arene …

Complexes of Ruthenium (II) as Promising Dual-Active Agents against Cancer and Viral Infections

A D'Amato, A Mariconda, D Iacopetta, J Ceramella… - Pharmaceuticals, 2023 - mdpi.com
Poor responses to medical care and the failure of pharmacological treatment for many high-
frequency diseases, such as cancer and viral infections, have been widely documented. In …

(Pentamethylcyclopentadienyl)chloridoiridium(III) Complex Bearing Bidentate Ph2PCH2CH2SPh-κPS Ligand

G Ludwig, I Ranđelović, D Dimić, T Komazec… - Biomolecules, 2024 - mdpi.com
The (pentamethylcyclopentadienyl) chloridoiridium (III) complex bearing a κ P, κ S-bonded
Ph2PCH2CH2SPh ligand ([Ir (η5-C5Me5) Cl (Ph2P (CH2) 2SPh-κ P, κ S)] PF6,(1)] was …

Novel cerium (IV) coordination compounds of monensin and salinomycin

N Petkov, I Pantcheva, A Ivanova, R Stoyanova… - Molecules, 2023 - mdpi.com
The largely uncharted complexation chemistry of the veterinary polyether ionophores,
monensic and salinomycinic acids (HL) with metal ions of type M4+ and the known …

Gastrointestinal cancer cells with Pt-resistance and relationship with aberrant expression of long non-coding RNAs

VA Ferretti, KL Klugh, KA Doucette, DC Crans… - Coordination Chemistry …, 2024 - Elsevier
The anticancer drugs cis-diamminedichloridoplatinum (II)(cisplatin) and oxaliplatin are
commonly used to treat patients with a number of cancers including gastrointestinal cancer …

Palladium (II) compounds containing oximes as promising antitumor agents for the treatment of osteosarcoma: An in vitro and in vivo comparative study with cisplatin

THR Pereira, TR de Moura, MRM Santos… - European Journal of …, 2024 - Elsevier
Drug resistance, evasion of cell death and metastasis are factors that contribute to the low
cure rate and disease-free survival in osteosarcomas (OS). In this study, we demonstrated …

[HTML][HTML] The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms

G Riegel, C Orvain, S Recberlik, ME Spaety, G Poschet… - Cancer Letters, 2024 - Elsevier
Platinum-based drugs remain the reference treatment for gastric cancer (GC). However, the
frequency of resistance, due to mutations in TP53 or alterations in the energy and redox …