The role of the epithelium in airway remodeling in asthma
DE Davies - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
The bronchial epithelium is the barrier to the external environment and plays a vital role in
protection of the internal milieu of the lung. It functions within the epithelial-mesenchymal …
protection of the internal milieu of the lung. It functions within the epithelial-mesenchymal …
Review on the development of genotyping methods for assessing farm animal diversity
Advances in molecular biotechnology have introduced new generations of molecular
markers for use in the genetic improvement of farm animals. Consequently, more accurate …
markers for use in the genetic improvement of farm animals. Consequently, more accurate …
Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma
H Jongepier, HM Boezen, A Dijkstra… - Clinical & …, 2004 - Wiley Online Library
Background Asthma is a genetically complex disease characterized by respiratory
symptoms, intermittent airway obstruction and airway hyper‐responsiveness due to airway …
symptoms, intermittent airway obstruction and airway hyper‐responsiveness due to airway …
A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population
CC van Diemen, DS Postma, JM Vonk… - American journal of …, 2005 - atsjournals.org
Rationale: A disintegrin and metalloprotease 33 (ADAM33) has been identified as a
susceptibility gene for asthma and single nucleotide polymorphisms (SNPs) in this gene …
susceptibility gene for asthma and single nucleotide polymorphisms (SNPs) in this gene …
[PDF][PDF] Molecular markers: An introduction and applications
FR Al-Samarai, AA Al-Kazaz - European journal of molecular …, 2015 - researchgate.net
It has introduced new generations of molecular markers for use in the genetic improvement
of farm animals. These markers provide more accurate genetic information and better …
of farm animals. These markers provide more accurate genetic information and better …
Increased expression of ADAM33 and ADAM8 with disease progression in asthma
SC Foley, AK Mogas, R Olivenstein, PO Fiset… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: ADAM33, a disintegrin and metalloproteinase 33 gene, has been identified
as a risk factor for asthma and bronchial hyperresponsiveness and has been postulated as a …
as a risk factor for asthma and bronchial hyperresponsiveness and has been postulated as a …
Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms
ST Holgate, DE Davies, RM Powell… - European …, 2007 - Eur Respiratory Soc
While asthma is an inflammatory disorder of the airways usually associated with atopy, an
important additional component is involvement of the epithelium and underlying …
important additional component is involvement of the epithelium and underlying …
Time to draw breath: asthma-susceptibility genes are identified
M Wills-Karp, SL Ewart - Nature Reviews Genetics, 2004 - nature.com
The prevalence of complex genetic immune disorders, such as asthma, arthritis and
diabetes, has escalated in recent decades. Despite the formidable challenges posed by the …
diabetes, has escalated in recent decades. Despite the formidable challenges posed by the …
Polymorphisms in A Disintegrin and Metalloprotease 33 (ADAM33) Predict Impaired Early-Life Lung Function
A Simpson, N Maniatis, F Jury… - American journal of …, 2005 - atsjournals.org
Rationale: Asthma commonly originates in early life in association with impaired lung
function, which tracks to adulthood. Objectives: Within the context of a prospective birth …
function, which tracks to adulthood. Objectives: Within the context of a prospective birth …
Genotyping single nucleotide polymorphisms by MALDI mass spectrometry in clinical applications
J Tost, IG Gut - Clinical biochemistry, 2005 - Elsevier
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
has become one of the most powerful and widely applied technologies for SNP scoring and …
has become one of the most powerful and widely applied technologies for SNP scoring and …