Recent aspects of the effects of zinc on human health

CT Chasapis, PSA Ntoupa, CA Spiliopoulou… - Archives of …, 2020 - Springer
Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …

A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

Zinc transporters and their functional integration in mammalian cells

T Kambe, KM Taylor, D Fu - Journal of Biological Chemistry, 2021 - ASBMB
Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …

Zinc in infection and inflammation

NZ Gammoh, L Rink - Nutrients, 2017 - mdpi.com
Micronutrient homeostasis is a key factor in maintaining a healthy immune system. Zinc is an
essential micronutrient that is involved in the regulation of the innate and adaptive immune …

Heavy metal and metalloid-induced reproductive toxicity

AG Mukherjee, UR Wanjari, K Renu, B Vellingiri… - Environmental …, 2022 - Elsevier
Heavy metals and metalloid exposure are among the most common factors responsible for
reproductive toxicity in human beings. Several studies have indicated that numerous metals …

Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases

S Choi, X Liu, Z Pan - Acta Pharmacologica Sinica, 2018 - nature.com
Zinc is an essential nutrient for human health and has anti-oxidative stress and anti-
inflammatory functions. The association between zinc deficiency and the development of …

Regulators of iron homeostasis: new players in metabolism, cell death, and disease

AR Bogdan, M Miyazawa, K Hashimoto… - Trends in biochemical …, 2016 - cell.com
Iron is necessary for life, but can also cause cell death. Accordingly, cells evolved a robust,
tightly regulated suite of genes for maintaining iron homeostasis. Previous mechanistic …

Brain manganese and the balance between essential roles and neurotoxicity

RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc in human health and infectious diseases

M Maywald, L Rink - Biomolecules, 2022 - mdpi.com
During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …