Tissue engineering and regenerative medicine: concepts for clinical application

A Atala - Rejuvenation research, 2004 - liebertpub.com
Patients suffering from diseased and injured organs may be treated with transplanted
organs. However, there is a severe shortage of donor organs that is worsening yearly given …

Calcium alginate gel: a biocompatible and mechanically stable polymer for endovascular embolization

TA Becker, DR Kipke, T Brandon - Journal of Biomedical …, 2001 - Wiley Online Library
The development and optimization of calcium alginate for potential use in endovascular
occlusion was investigated by testing its in vitro and in vivo mechanical stability and …

Considerations for successful transplantation of encapsulated pancreatic islets

P De Vos, AF Hamel, K Tatarkiewicz - Diabetologia, 2002 - Springer
Encapsulation of pancreatic islets allows for transplantion in the absence of
immunosuppression. The technology is based on the principle that transplanted tissue is …

[HTML][HTML] Islet transplantation and encapsulation: an update on recent developments

V Vaithilingam, BE Tuch - The review of diabetic studies: RDS, 2011 - ncbi.nlm.nih.gov
Human islet transplantation can provide good glycemic control in diabetic recipients without
exogenous insulin. However, a major factor limiting its application is the recipient's need to …

Poly-L-lysine induces fibrosis on alginate microcapsules via the induction of cytokines

BL Strand, L Ryan, PI Veld, B Kulseng… - Cell …, 2001 - journals.sagepub.com
Alginate–poly-l-lysine (PLL) microcapsules can be used for transplantation of insulin-
producing cells for treatment of type I diabetes. In this work we wanted to study the …

Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation

AMA Rokstad, I Lacik, P de Vos, BL Strand - Advanced drug delivery …, 2014 - Elsevier
Cell encapsulation has already shown its high potential and holds the promise for future cell
therapies to enter the clinics as a large scale treatment option for various types of diseases …

Multiscale requirements for bioencapsulation in medicine and biotechnology

P de Vos, M Bučko, P Gemeiner, M Navrátil, J Švitel… - Biomaterials, 2009 - Elsevier
Bioencapsulation involves the envelopment of tissues or biological active substances in
semipermeable membranes. Bioencapsulation has been shown to be efficacious in …

Complete monosaccharide analysis by high-performance anion-exchange chromatography with pulsed amperometric detection

Z Zhang, NM Khan, KM Nunez, EK Chess… - Analytical …, 2012 - ACS Publications
Monosaccharide analysis is a critical way to profile the composition of complex
carbohydrates. Methods to analyze neutral and amino sugars have been established for a …

Hydrogels used for cell‐based drug delivery

JJ Schmidt, J Rowley, HJ Kong - … Part A: An Official Journal of …, 2008 - Wiley Online Library
Stem cells, progenitor cells, and lineage‐committed cells are being considered as a new
generation of drug depots for the sustained release of therapeutic biomolecules. Hydrogels …

Anti-inflammatory peptide-functionalized hydrogels for insulin-secreting cell encapsulation

J Su, BH Hu, WL Lowe Jr, DB Kaufman… - Biomaterials, 2010 - Elsevier
Pancreatic islet encapsulation within semi-permeable materials has been proposed for
transplantation therapy of type I diabetes mellitus. Polymer hydrogel networks used for this …