Patients suffering from diseased and injured organs may be treated with transplanted
organs; however, there is a severe shortage of donor organs that is worsening yearly, given …

Islet transplantation may be used to treat type I diabetes. Despite tremendous progress in
islet isolation, culture, and preservation, the clinical use of this modality of treatment is …

Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in
semipermeable but immunoprotective polymeric membranes. The technology allows for …

This review is focused on the materials and methods used to fabricate closed‐loop systems
for type 1 diabetes therapy. Herein, we give a brief overview of current methods used for …

Conventional materials technology has yielded clear improvements in regenerative
medicine. Ideally, however, a replacement material should mimic the living tissue …

As one of the major components of regenerative medicine, tissue engineering follows the
principles of cell transplantation, materials science, and engineering toward the …

The survival of microencapsulated islet grafts is limited, even if capsular overgrowth is
restricted to a small percentage of the capsules. In search of processes other than …

The encapsulation of cells into polymeric microspheres or microcapsules has permitted the
transplantation of cells into human and animal subjects without the need for …

Transplantation of pancreatic islets encapsulated within immuno-protective microcapsules is
a strategy that has the potential to overcome graft rejection without the need for toxic …

Successful transplantation of pancreatic tissue has been demonstrated to be an efficacious
method of restoring glycemic control in type 1 diabetic patients. To establish graft …