In vivo characterization of a porous hydrogel material for use as a tissue bulking agent

A Loebsack, K Greene, S Wyatt… - … Research: An Official …, 2001 - Wiley Online Library
Tissue engineered biomaterial constructs are needed for plastic and reconstructive
applications. To successfully form a space‐filling tissue, the construct should induce a …

The association between in vivo physicochemical changes and inflammatory responses against alginate based microcapsules

P de Vos, M Spasojevic, BJ de Haan, MM Faas - Biomaterials, 2012 - Elsevier
Application of alginate-polylysine (PLL) capsules for immunoisolation of living cells are
suffering from a varying degree of success and large lab-to-lab variations. In this study we …

Improving alginate‐poly‐L‐ornithine‐alginate capsule biocompatibility through genipin crosslinking

AL Hillberg, K Kathirgamanathan… - … Research Part B …, 2013 - Wiley Online Library
DIABECELL® capsules comprise an inner core of alginate (Alg) coated with a polycationic
polymer, poly‐l‐ornithine (PLO), designed as a stabilizing agent for strengthening the …

Biomaterials and tissue engineering

SJ Lee, JJ Yoo, A Atala - Clinical regenerative medicine in urology, 2018 - Springer
Tissue engineering, a major technique in regenerative medicine, follows the principles of
cell biology, materials science, and engineering to develop biological substitutes that mimic …

Preparation of injectable 3D-formed β-tricalcium phosphate bead/alginate composite for bone tissue engineering

T Matsuno, Y Hashimoto, S Adachi, K Omata… - Dental materials …, 2008 - jstage.jst.go.jp
A novel, injectable bone tissue engineering material was developed that consisted of β-
tricalcium phosphate (β-TCP) beads as the solid phase and alginate as the gel phase. To …

A strategy to passively reduce neuroinflammation surrounding devices implanted chronically in brain tissue by manipulating device surface permeability

JL Skousen, MJ Bridge, PA Tresco - Biomaterials, 2015 - Elsevier
Available evidence indicates that pro-inflammatory cytokines produced by immune cells are
likely responsible for the negative sequela associated with the foreign body response (FBR) …

Flow properties of liquid calcium alginate polymer injected through medical microcatheters for endovascular embolization

TA Becker, DR Kipke - … Research: An Official Journal of The …, 2002 - Wiley Online Library
The flow properties of liquid calcium alginate injections were investigated for application in
endovascular embolization. Alginate shear properties were assessed with a rheometer and …

In vitro and in vivo evaluation of alginate/sol–gel synthesized aminopropyl-silicate/alginate membrane for bioartificial pancreas

S Sakai, T Ono, H Ijima, K Kawakami - Biomaterials, 2002 - Elsevier
Alginate/aminopropyl-silicate/alginate (Alg/AS/Alg) membrane was prepared on Ca-alginate
gel beads by a sol–gel process. The membrane has≡ Si–O–Si≡ bonds as well as …

Hydrogel-based non-autologous cell and tissue therapy

U Zimmermann, S Mimietz, H Zimmermann… - …, 2000 - Taylor & Francis
Many diseases are closely tied to deficient or subnormal metabolic and secretory cell
functions. Milder forms of these diseases can be managed by a variety of treatments …

Tissue responses against immunoisolating alginate‐PLL capsules in the immediate posttransplant period

P De Vos, CG van Hoogmoed… - … Research: An Official …, 2002 - Wiley Online Library
Alginate‐polylysine (PLL) capsules are commonly applied for immunoisolation of living cells
for the treatment of a wide variety of diseases. Large‐scale application of the technique …