Engineered cell-laden alginate microparticles for 3D culture
Advanced microfabrication technologies and biocompatible hydrogel materials facilitate the
modeling of 3D tissue microenvironment. Encapsulation of cells in hydrogel microparticles …
modeling of 3D tissue microenvironment. Encapsulation of cells in hydrogel microparticles …
Development of mechanically stable alginate/chondrocyte constructs: effects of guluronic acid content and matrix synthesis
M Wong, M Siegrist, X Wang… - Journal of Orthopaedic …, 2001 - Wiley Online Library
The purpose of this study was to investigate factors which enhanced the compressive
properties of alginate/chondrocyte constructs. Firstly, we studied the effect of biochemical …
properties of alginate/chondrocyte constructs. Firstly, we studied the effect of biochemical …
Association between macrophage activation and function of micro-encapsulated rat islets
P De Vos, I Smedema, H Van Goor, H Moes… - Diabetologia, 2003 - Springer
Aims/hypothesis Survival of microencapsulated islet grafts is limited, even when
inflammatory reactions against the capsules are restricted to a small portion of less than …
inflammatory reactions against the capsules are restricted to a small portion of less than …
Microencapsulation of cells producing therapeutic proteins: optimizing cell growth and secretion
AM Rokstad, S Holtan, B Strand… - Cell …, 2002 - journals.sagepub.com
Microencapsulation of genetically engineered cells may have important applications as
delivery systems for therapeutic proteins. However, optimization of the microcapsules with …
delivery systems for therapeutic proteins. However, optimization of the microcapsules with …
Improvement of the biocompatibility of alginate/poly‐L‐lysine/alginate microcapsules by the use of epimerized alginate as a coating
Abstract Alginate/poly‐l‐lysine (PLL)/alginate capsules are used widely for the
microencapsulation of cells. Alginate consists of guluronic acid and mannuronic acid, the …
microencapsulation of cells. Alginate consists of guluronic acid and mannuronic acid, the …
Long-term function of alginate-encapsulated islets
M Köllmer, AA Appel, SI Somo… - Tissue Engineering Part B …, 2016 - liebertpub.com
Human trials have demonstrated the feasibility of alginate-encapsulated islet cells for the
treatment of type 1 diabetes. Encapsulated islets can be protected from the host's immune …
treatment of type 1 diabetes. Encapsulated islets can be protected from the host's immune …
Biocompatibility investigation of polyethylene glycol and alginate-poly-L-lysine for islet encapsulation
XY Liu, JM Nothias, A Scavone, M Garfinkel… - ASAIO …, 2010 - journals.lww.com
The use of microencapsulation with alginate-poly-l-lysine (PLL) as the encapsulation
material has been hampered by overgrowth of collagen around implanted capsules. Studies …
material has been hampered by overgrowth of collagen around implanted capsules. Studies …
Characterization of alginate/poly-L-lysine particles as antisense oligonucleotide carriers
MG Ferreiro, L Tillman, G Hardee… - International Journal of …, 2002 - Elsevier
The gel forming characteristics of alginate in the presence of calcium ions and further
crosslinking with poly-l-lysine led to the formation of sponge-like nano-and microparticles …
crosslinking with poly-l-lysine led to the formation of sponge-like nano-and microparticles …
Alginate-based microencapsulation of retinal pigment epithelial cell line for cell therapy
J Wikström, M Elomaa, H Syväjärvi, J Kuokkanen… - Biomaterials, 2008 - Elsevier
The goals of this study were to evaluate human retinal pigment epithelial cell line (ARPE-19)
for cell encapsulation and to optimize the alginate-based microencapsulation. We used …
for cell encapsulation and to optimize the alginate-based microencapsulation. We used …
Zeta‐potentials of alginate‐PLL capsules: a predictive measure for biocompatibility?
P de Vos, BJ de Haan, JAAM Kamps… - … research Part A, 2007 - Wiley Online Library
Abstract Alginate‐poly‐l‐lysine (PLL) microencapsulation of cells is a promising approach to
prevent rejection in the absence of immunosuppression. Clinical application, however, is …
prevent rejection in the absence of immunosuppression. Clinical application, however, is …