The progress of precision oncology medicine is always limited by the tumor off‐targeting, the
drug side effects, and the treatment inefficiency due to the complex and ever‐changing …

Costimulatory receptors on immune cells represent attractive targets for immunotherapy
given that these molecules can increase the frequency of individual protective immune cell …

Engineered T cells hold great promise to become part of an effective HIV cure strategy, but it
is currently unclear how best to redirect T cells to target HIV. To gain insight, we generated …

Following the success of dendritic cell (DC) vaccine, cell‐based tumor vaccine shows its
promise as a vaccination strategy. Except for DC cells, targeting other immune cells …

T cells play a crucial role in antitumor immune responses and the clearance of infected cells.
They identify their targets through the binding of T-cell receptors (TCRs) to peptide–major …

Current Opinion in HIV and AIDS Log in or Register Subscribe to journalSubscribe Get new
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The inability of people living with HIV (PLWH) to eradicate human immunodeficiency virus
(HIV) infection is due in part to the inadequate HIV-specific cellular immune response. The …

Immunotherapeutic modulation of antigen‐specific T‐cell responses instead of the whole
repertoire helps avoid immune‐related adverse events. We have developed an artificial …

Abstract Purpose of Review Human cytomegalovirus (HCMV), while asymptomatic in most,
causes significant complications during fetal development, following transplant or in …

Although the world is currently focused on the COVID-19 pandemic, HIV/AIDS remains a
significant threat to public health. To date, the HIV/AIDS pandemic has claimed the lives of …