Extracellular vesicles and their indispensable roles in pathogenesis and treatment of inflammatory bowel disease: A comprehensive review

L Chen, Q Ou, X Kou - Life Sciences, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a global disease with rising incidence worldwide, and
its debilitating symptoms and dissatisfactory therapies have brought heavy burdens for …

[HTML][HTML] Human retinal secretome: A cross-link between mesenchymal and retinal cells

L Donato, C Scimone, S Alibrandi… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
In recent years, mesenchymal stem cells (MSC) have been considered the most effective
source for regenerative medicine, especially due to released soluble paracrine bioactive …

Gentisic acid ameliorates type 2 diabetes induced by Nicotinamide-Streptozotocin in male mice by attenuating pancreatic oxidative stress and inflammation through …

RN Razliqi, A Ahangarpour, SA Mard, L Khorsandi - Life Sciences, 2023 - Elsevier
Aims There is a close link between oxidative stress, inflammation, and type 2 diabetes
mellitus (T2DM). Gentisic acid (GA) is a di-phenolic compound and an active metabolite of …

Synergistic effects of mesenchymal stem cell-derived extracellular vesicles and dexamethasone on macrophage polarization under inflammatory conditions

Z Mirsanei, F Jamshidi-Adegani, S Vakilian… - …, 2024 - Springer
The undesirable inflammation and the excessive M1 macrophage activity may lead to
inflammatory diseases. Corticosteroids and stem cell therapy are used in clinical practice to …

[HTML][HTML] Could extracellular vesicles derived from mesenchymal stem cells be a potential therapy for acute pancreatitis-induced cardiac injury?

LF Pan, ZQ Niu, S Ren, HH Pei, YX Gao… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant
challenges in the treatment of severe AP and contributing to increased mortality rates …

Epigenetic biomarkers in aging and longevity: Current and future application

M Izadi, N Sadri, A Abdi, S Serajian, D Jalalei… - Life Sciences, 2024 - Elsevier
The aging process has been one of the most necessary research fields in the current
century, and knowing different theories of aging and the role of different genetic, epigenetic …

Exploring Cutting-Edge Approaches to Potentiate Mesenchymal Stem Cell and Exosome Therapy for Myocardial Infarction

C Peng, J Yan, Y Jiang, L Wu, M Li, X Fan - Journal of Cardiovascular …, 2024 - Springer
Cardiovascular diseases (CVDs) continue to be a significant global health concern. Many
studies have reported promising outcomes from using MSCs and their secreted exosomes in …

TLR3 Agonist Amplifies the Anti‐Inflammatory Potency of ADSCs via IL‐10‐Mediated Macrophage Polarization in Acute Pancreatitis

J Liu, W Yan, S Chen, Y Sun, F Zhang… - Stem Cells …, 2024 - Wiley Online Library
The immunoregulatory role of mesenchymal stem cells (MSCs) in inflammation is
heterogeneous and can exhibit anti‐inflammatory or proinflammatory properties depending …

Inhibition of cGAS-STING pathway by stress granules after activation of M2 macrophages by human mesenchymal stem cells against drug induced liver injury

Y Wang, S She, W Li, J Zhu, X Li, F Yang, K Dai - Molecular Immunology, 2024 - Elsevier
Objective Cells can produce stress granules (SGs) to protect itself from damage under
stress. The cGAS-STING pathway is one of the important pattern recognition pathways in the …

Advancements in the study of acute lung injury resulting from intestinal ischemia/reperfusion

S Lv, X Zhao, C Ma, D Zhao, T Sun, W Fu, Y Wei… - Frontiers in …, 2024 - frontiersin.org
Intestinal ischemia/reperfusion is a prevalent pathological process that can result in
intestinal dysfunction, bacterial translocation, energy metabolism disturbances, and …