miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways

AS Doghish, AI Abulsoud, SS Elshaer… - … -Research and Practice, 2023 - Elsevier
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …

A comparison of the International Consensus and 5th World Health Organization classifications of mature B-cell lymphomas

B Falini, G Martino, S Lazzi - Leukemia, 2023 - nature.com
Several editions of the World Health Organization (WHO) classifications of lympho-
hemopoietic neoplasms in 2001, 2008 and 2017 served as the international standard for …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma

C Melani, R Lakhotia, S Pittaluga… - … England Journal of …, 2024 - Mass Medical Soc
Background The identification of oncogenic mutations in diffuse large B-cell lymphoma
(DLBCL) has led to the development of drugs that target essential survival pathways, but …

Global burden of hematologic malignancies and evolution patterns over the past 30 years

N Zhang, J Wu, Q Wang, Y Liang, X Li, G Chen… - Blood Cancer …, 2023 - nature.com
Hematologic malignancies are among the most common cancers, and understanding their
incidence and death is crucial for targeting prevention, clinical practice improvement, and …

New concepts in EBV-associated B, T, and NK cell lymphoproliferative disorders

L Quintanilla-Martinez, SH Swerdlow, T Tousseyn… - Virchows Archiv, 2023 - Springer
EBV-associated lymphoproliferative disorders (LPD) include conditions of B, T, and NK cell
derivation with a wide clinicopathological spectrum ranging from indolent, self-limiting, and …

Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population

W Alduaij, B Collinge, S Ben-Neriah… - Blood, The Journal …, 2023 - ashpublications.org
Molecular heterogeneity of diffuse large B-cell lymphoma (DLBCL) underlies the variable
outcomes achieved with immunochemotherapy. However, outcomes of gene expression …

Chronic lymphocytic leukemia treatment algorithm 2022

PJ Hampel, SA Parikh - Blood cancer journal, 2022 - nature.com
The treatment landscape for patients with chronic lymphocytic leukemia (CLL) has changed
considerably with the introduction of very effective oral targeted therapies (such as Bruton …

Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management

AC Hristov, T Tejasvi, RA Wilcox - American journal of …, 2023 - Wiley Online Library
Abstract Disease Overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐
cell neoplasms involving the skin, the majority of which may be classified as Mycosis …

Plasma cell neoplasms and related entities—evolution in diagnosis and classification

F Fend, A Dogan, JR Cook - Virchows Archiv, 2023 - Springer
Plasma cell neoplasms including multiple myeloma (MM) and related terminally
differentiated B-cell neoplasms are characterized by secretion of monoclonal …