Exosomes in cancer nanomedicine and immunotherapy: prospects and challenges

NL Syn, L Wang, EKH Chow, CT Lim, BC Goh - Trends in biotechnology, 2017 - cell.com
Exosomes (versatile, cell-derived nanovesicles naturally endowed with exquisite target-
homing specificity and the ability to surmount in vivo biological barriers) hold substantial …

[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …

Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players

NI Rizk, AI Abulsoud, MM Kamal, DH Kassem… - Life sciences, 2022 - Elsevier
Exosomes are nano-vesicles (NVs) secreted by cells and take part in cell-cell
communications. Lately, these exosomes were proved to have dual faces in cancer …

Exosomes as drug carriers for cancer therapy

JE Pullan, MI Confeld, JK Osborn, J Kim… - Molecular …, 2019 - ACS Publications
Exosomes, biological extracellular vesicles, have recently begun to find use in targeted drug
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …

[HTML][HTML] Inclusion biogenesis, methods of isolation and clinical application of human cellular exosomes

M Tschuschke, I Kocherova, A Bryja… - Journal of clinical …, 2020 - mdpi.com
Exosomes are a heterogenous subpopulation of extracellular vesicles 30–150 nm in range
and of endosome-derived origin. We explored the exosome formation through different …

Recent advances in nanoparticle-based cancer drug and gene delivery

N Amreddy, A Babu, R Muralidharan… - Advances in cancer …, 2018 - Elsevier
Effective and safe delivery of anticancer agents is among the major challenges in cancer
therapy. The majority of anticancer agents are toxic to normal cells, have poor bioavailability …

[HTML][HTML] Trends in research on exosomes in cancer progression and anticancer therapy

D Sinha, S Roy, P Saha, N Chatterjee, A Bishayee - Cancers, 2021 - mdpi.com
Simple Summary Intensive research in the field of cancer biology has discovered a unique
mode of interplay between cells via extracellular bioactive vesicles called exosomes …

Current advances in the use of exosomes, liposomes, and bioengineered hybrid nanovesicles in cancer detection and therapy

A Mukherjee, B Bisht, S Dutta, MK Paul - Acta Pharmacologica Sinica, 2022 - nature.com
Three major approaches of cancer therapy can be enunciated as delivery of biotherapeutics,
tumor image analysis, and immunotherapy. Liposomes, artificial fat bubbles, are long known …

[HTML][HTML] Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …

Subpopulations of extracellular vesicles and their therapeutic potential

C Lässer, SC Jang, J Lötvall - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …