[HTML][HTML] Frailty and diabetes in older adults: Overview of current controversies and challenges in clinical practice

MZA Abd. Ghafar, M O'Donovan, D Sezgin… - Frontiers in Clinical …, 2022 - frontiersin.org
This article examines the challenges healthcare professionals face when addressing the
modern and often twin epidemics of frailty and diabetes mellitus (DM) in ageing societies …

[HTML][HTML] Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

[HTML][HTML] Is inflammatory signaling involved in disease-related muscle wasting? Evidence from osteoarthritis, chronic obstructive pulmonary disease and type II …

S Dalle, K Koppo - Experimental gerontology, 2020 - Elsevier
Muscle loss is an important feature that occurs in multiple pathologies including
osteoarthritis (OA), chronic obstructive pulmonary disease (COPD) and type II diabetes …

[HTML][HTML] The vicious cycle of type 2 diabetes mellitus and skeletal muscle atrophy: clinical, biochemical, and nutritional bases

JM Lopez-Pedrosa, M Camprubi-Robles… - Nutrients, 2024 - mdpi.com
Today, type 2 diabetes mellitus (T2DM) and skeletal muscle atrophy (SMA) have become
increasingly common occurrences. Whether the onset of T2DM increases the risk of SMA or …

Sarcopenia in a type 2 diabetic state: reviewing literature on the pathological consequences of oxidative stress and inflammation beyond the neutralizing effect of …

N Muvhulawa, SE Mazibuko-Mbeje, D Ndwandwe… - Life Sciences, 2023 - Elsevier
Sarcopenia remains one of the major pathological features of type 2 diabetes (T2D),
especially in older individuals. This condition describes gradual loss of muscle mass …

[HTML][HTML] Bibliometric analysis of the knowledge base and future trends on sarcopenia from 1999–2021

Y Xiao, Z Deng, H Tan, T Jiang, Z Chen - International Journal of …, 2022 - mdpi.com
Sarcopenia is characterized by progressive loss of muscle mass and function, and it is
becoming a serious public health problem with the aging population. However, a …

[HTML][HTML] Type 2 diabetes mellitus and sarcopenia as comorbid chronic diseases in older adults: established and emerging treatments and therapies

J Mesinovic, JJ Fyfe, J Talevski… - … & Metabolism Journal, 2023 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) and sarcopenia (low skeletal muscle mass and function)
share a bidirectional relationship. The prevalence of these diseases increases with age and …

[HTML][HTML] Identification of the shared gene signatures and pathways between sarcopenia and type 2 diabetes mellitus

S Huang, C Xiang, Y Song - PLoS One, 2022 - journals.plos.org
Background Sarcopenia is characterized by the age-associated loss of skeletal muscle
mass and strength that develops progressively and plays an important role in the disability of …

[HTML][HTML] Shared and divergent epigenetic mechanisms in cachexia and sarcopenia

L Yedigaryan, M Gatti, V Marini, T Maraldi… - Cells, 2022 - mdpi.com
Significant loss of muscle mass may occur in cachexia and sarcopenia, which are major
causes of mortality and disability. Cachexia represents a complex multi-organ syndrome …

Targeting the incretin system in obesity and type 2 diabetes mellitus

S Ansari, B Khoo, T Tan - Nature Reviews Endocrinology, 2024 - nature.com
Obesity and type 2 diabetes mellitus (T2DM) are widespread, non-communicable diseases
that are responsible for considerable levels of morbidity and mortality globally, primarily in …