Since its inception, the coronavirus disease 2019 (COVID‐19) pandemic has infected
millions of people around the world. Therefore, it is necessary to find effective treatments …

Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Cytisine, a natural bioactive compound that is mainly isolated from plants of the
Leguminosae family (especially the seeds of Laburnum anagyroides), has been marketed in …

For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Numerous eight-membered heterocycles are of significance in biological chemistry, the
pharmaceutical industry, agrochemistry, and materials science. However, the assembly of …

A novel coronavirus, SARS-CoV-2, emerged in China at the end of 2019 causing a large
global outbreak. As treatments are of the utmost importance, drugs with broad anti …

Testicular germ cell tumors share a marked sensitivity to cisplatin, contributing to their
overall good prognosis. However, a subset of patients develop resistance to platinum-based …

Dengue virus (DENV) causes about 50–100 million cases per year worldwide. However,
there is still a big challenge in developing antiviral drugs against DENV infection. Some …

Postmenopausal Osteoporosis (PMOP) is oestrogen withdrawal characterized of much
production and activation by osteoclast in the elderly female. Cytisine is a quinolizidine …

Asarum heterotropoides var. mandshuricum F. Maekawa (Aristolochiaceae), well-known as
“Marchurian Wildginger”, shows many bioactivities that contribute to its therapeutic effects …