[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Corneal neovascularization

MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …

BCLA CLEAR-Contact lens complications

F Stapleton, M Bakkar, N Carnt, R Chalmers… - Contact Lens and …, 2021 - Elsevier
Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

Corneal stromal wound healing: Major regulators and therapeutic targets

S Kamil, RR Mohan - The ocular surface, 2021 - Elsevier
Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

[HTML][HTML] Corneal neovascularization: updates on pathophysiology, investigations & management

Z Sharif, W Sharif - Romanian journal of ophthalmology, 2019 - ncbi.nlm.nih.gov
Objective. Corneal neovascularization is a sight-threatening condition affecting more than
1.4 million people per year. Left untreated, it can lead to tissue scarring, oedema, lipid …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Regulatory T cells in angiogenesis

Z Lužnik, S Anchouche, R Dana, J Yin - The Journal of Immunology, 2020 - journals.aai.org
Regulatory T cells (Tregs) are crucial mediators of immune homeostasis. They regulate
immune response by suppressing inflammation and promoting self-tolerance. In addition to …

[HTML][HTML] Pathogenesis of herpes stromal keratitis: immune inflammatory response mediated by inflammatory regulators

L Wang, R Wang, C Xu, H Zhou - Frontiers in Immunology, 2020 - frontiersin.org
Herpes stromal keratitis (HSK) is one of the primary diseases that cause vision loss or even
blindness after herpes simplex virus (HSV)-1 infection. HSK-associated vision impairment is …

Biomimetic corneal stroma for scarless corneal wound healing via structural restoration and microenvironment modulation

J Huang, T Jiang, J Li, J Qie, X Cheng… - Advanced …, 2024 - Wiley Online Library
Corneal injury‐induced stromal scarring causes the most common subtype of corneal
blindness, and there is an unmet need to promote scarless corneal wound healing. Herein …

BCLA CLEAR-Effect of contact lens materials and designs on the anatomy and physiology of the eye

PB Morgan, PJ Murphy, KL Gifford, P Gifford… - Contact Lens and …, 2021 - Elsevier
This paper outlines changes to the ocular surface caused by contact lenses and their degree
of clinical significance. Substantial research and development to improve oxygen …