[HTML][HTML] Using chitosan or chitosan derivatives in cancer therapy

MS Shakil, KM Mahmud, M Sayem, MS Niloy… - Polysaccharides, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide. Chemotherapeutic drugs have
become a popular choice as anticancer agents. Despite the therapeutic benefits of …

Temperature responsive hydrogel for cells encapsulation based on graphene oxide reinforced poly (N-isopropylacrylamide)/hydroxyethyl-chitosan

L Nie, J Li, G Lu, X Wei, Y Deng, S Liu, S Zhong… - Materials Today …, 2022 - Elsevier
Temperature-responsive hydrogels exhibit great potentials to encapsulate cells for 3D
bioprinting and tissue engineering applications; however, cell aggregation and the hydrogel …

Decellularized plant-derived vasculature-on-a-chip interacting with breast cancer spheroids to evaluate a dual-drug therapy

Y Filiz, Y Arslan, E Duran, P Saglam-Metiner… - Applied Materials …, 2024 - Elsevier
Breast cancer progression is a complex process involving the primary tumor and its
microenvironment supported by a vascular network. Multicellular spheroids closely mimic in …

A three dimensional in vivo model of breast cancer using a thermosensitive chitosan‐based hydrogel and 4 T1 cell line in Balb/c

L Rezakhani, M Alizadeh… - Journal of Biomedical …, 2021 - Wiley Online Library
Abstract The two‐dimensional (2D) models of breast cancer still exhibit a limited success.
Whereas, three‐dimensional (3D) models provide more similar conditions to the tumor for …

Recapitulating spatiotemporal tumor heterogeneity in vitro through engineered breast cancer microtissues

C Mazio, C Casale, G Imparato, F Urciuolo, PA Netti - Acta Biomaterialia, 2018 - Elsevier
Tumor and microenvironmental heterogeneity hinders the study of breast cancer biology
and the assessment of therapeutic strategies, being associated with high variability and drug …

[HTML][HTML] Embedded Living HER2+ Cells in a 3D Gelatin–Alginate Hydrogel as an In Vitro Model for Immunotherapy Delivery for Breast Cancer

GT De Dios-Figueroa, JR Aguilera-Márquez… - Polymers, 2023 - mdpi.com
Epidermal growth factor receptor 2 (HER2) is the second target molecule most commonly
used in breast cancer treatment. Both recurrence and metastasis are still deadly for HER2+ …

[HTML][HTML] Cell behavioral changes after the application of magneto-mechanical activation to normal and cancer cells

AR Tsiapla, V Uzunova, T Oreshkova, M Angelakeris… - Magnetochemistry, 2022 - mdpi.com
In vitro cell exposure to nanoparticles, depending on the applied concentration, can help in
the development of theranostic tools to better detect and treat human diseases. Recent …

Design of synthetic extracellular matrices for probing breast cancer cell growth using robust cyctocompatible nucleophilic thiol-yne addition chemistry

LJ Macdougall, KL Wiley, AM Kloxin, AP Dove - Biomaterials, 2018 - Elsevier
Abstract Controlled, three-dimensional (3D) cell culture systems are of growing interest for
both tissue regeneration and disease, including cancer, enabling hypothesis testing about …

[HTML][HTML] Acetylacetone and imidazole coordinated Re (I) tricarbonyl complexes: Experimental, DFT studies, and molecular docking approach

ALE Manicum, H Louis, EC Agwamba, CM Chima… - Chemical Physics …, 2023 - Elsevier
The research work presents the synthesis, spectral characterization (UV, FT-IR, and NMR),
and modelling of tricarbonyl rhenium complexes (R1, R2, R3, R4, and R5) bearing the β …

[HTML][HTML] Synergistic effect of combined treatment with magnetic hyperthermia and magneto-mechanical stress of breast cancer cells

R Tzoneva, AR Tsiapla, V Uzunova, T Stoyanova… - Magnetochemistry, 2022 - mdpi.com
With the development of nanotechnology, the emergence of new anti-tumor techniques
using nanoparticles such as magnetic hyperthermia and magneto-mechanical activation …