The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

Endothelial dysfunction is a systemic disorder and a key variable in the pathogenesis of
atherosclerosis and its complications. Current evidence suggests that endothelial status is …

Hypertension is characterized by structural and functional changes in blood vessels that
travel with increased arterial stiffness, vascular inflammation, and endothelial dysfunction …

The endothelium, once considered a mere selectively permeable barrier between the
bloodstream and the outer vascular wall, is now recognized to be a crucial homeostatic …

Diabetes mellitus is associated with an increased risk of cardiovascular disease, even in the
presence of intensive glycemic control. Substantial clinical and experimental evidence …

Endothelial cells synthesize and release various factors that regulate angiogenesis,
inflammatory responses, hemostasis, as well as vascular tone and permeability. Endothelial …

Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated
with atherosclerosis and is therefore held to be an early feature in atherogenesis. However …

Background—Studies in selected samples have linked impaired endothelial function with
cardiovascular disease and its risk factors. The clinical correlates and heritability of …

Endothelial function, assessed using brachial artery flow-mediated dilation (FMD), predicts
future cardiovascular disease (CVD) risk. This study established age-and sex-specific …

To compare the effect of antihypertensive drugs on endothelium-dependent vasodilation in
the peripheral conduit arteries of patients with essential hypertension, in a prospective …