Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Immunotherapy based on immune checkpoint inhibitors (ICIs) has revolutionized treatment
strategies in multiple types of cancer. However, the resistance and relapse as associated …

Background Methylation of cytosine residues resulting in 5-methylcytosine (5-mC) is an
important epigenetic modification associated with tumorigenesis. The present study …

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with
a poor prognosis. 5-methylcytosine (m5C) modification plays a nonnegligible role in tumor …

Background: Pancreatic adenocarcinoma (PAAD) is one of the most malignant cancers and
has a poor prognosis. As a critical RNA modification, 5-methylcytosine (m5C) has been …

DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …

Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates found in sites of chronic
inflammation such as tumors and autoimmune diseases. The discovery that TLS formation at …

Abstract Fine particulate matter (PM2. 5) increases the risks of lung cancer. Epigenetics
provides a new toxicology mechanism for the adverse health effects of PM2. 5. However, the …

Aberrant patterns of 5-methylcytosine (m5C)-based ribonucleic acid (RNA) methylation have
critical roles in various human diseases, but their importance in spinal cord injury (SCI) is …