Shining a light on prostate cancer: photodynamic therapy and combination approaches

H Wahnou, I Youlyouz-Marfak, B Liagre, V Sol… - Pharmaceutics, 2023 - mdpi.com
Prostate cancer is a major health concern worldwide, and current treatments, such as
surgery, radiation therapy, and chemotherapy, are associated with significant side effects …

Cancer metabolism: the role of ROS in DNA damage and induction of apoptosis in Cancer Cells

Y Zhao, X Ye, Z Xiong, A Ihsan, I Ares, M Martínez… - Metabolites, 2023 - mdpi.com
Cancer is a huge challenge for people worldwide. High reactive oxygen species (ROS)
levels are a recognized hallmark of cancer and an important aspect of cancer treatment …

pH-responsive dual-drug nanomicelles for co-delivery of DOX and Ce6 for combination therapy of tumors

M Liu, J Lei, K Yuan, Y Zhao, J Zhang, D Li… - Journal of Drug Delivery …, 2023 - Elsevier
In this study, pH-responsive nanomicelles were constructed to co-deliver the
chemotherapeutic drug doxorubicin (DOX) and the photosensitizer chlorin e6 (Ce6). The …

Thioglycerol-porphyrin,-chlorin, and-phthalocyanine derivatives for photodynamic therapy of UM-UC-3 bladder cancer cells

LMO Lourenço, S Beirão, A Melo, R Fernandes… - … of Photochemistry and …, 2023 - Elsevier
Photodynamic Therapy (PDT) has been successfully used to treat different tumour types
since its approval. However, the search for more powerful and selective photosensitisers …

Photodynamic Therapy-Induced Anti-Tumor Immunity: Influence Factors and Synergistic Enhancement Strategies

W Chou, T Sun, N Peng, Z Wang, D Chen, H Qiu… - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic
activity towards tumor cells by activating photosensitizers (PSs) with light exposure to …

Tumor-associated macrophages affect the treatment of lung cancer

Z Yu, J Zou, F Xu - Heliyon, 2024 - cell.com
As one of the most common malignant tumors in the world, lung cancer has limited benefits
for patients despite its diverse treatment methods due to factors such as personalized …

[HTML][HTML] Cepharanthine synergizes with photodynamic therapy for boosting ROS-driven DNA damage and suppressing MTH1 as a potential anti-cancer strategy

ZY Yang, LG Li, YL Xiong, NN Chen, TT Yu… - Photodiagnosis and …, 2024 - Elsevier
Objective Photodynamic therapy (PDT) primarily treats skin diseases or cancer by
generating reactive oxygen species (ROS) to damage cellular DNA, yet drug resistance …

Stearyl palmitate a multi-target inhibitor against breast cancer: in-silico, in-vitro & in-vivo approach

L Ravi, A Kumar K, S Kumari GR… - Journal of …, 2023 - Taylor & Francis
Multi-target inhibitors are currently trending in the pharmaceutical research, as they possess
increased efficacy and reduced toxicity. In this study multi-target inhibitors for breast cancer …