Cardiovascular diseases (CVDs), which encompass a myriad of pathological conditions that
affect the heart and/or the blood vessels, remain the major cause of morbidity and mortality …

Classically associated with gap junction-mediated intercellular communication, connexin43
(Cx43) is increasingly recognized to possess non-canonical biological functions, including …

Cell-to-cell communication plays a cardinal role in the biology of multicellular organisms. H
2 O 2 is an important cell-to-cell signaling molecule involved in the response of mammalian …

Pathological reprogramming of cardiomyocyte and fibroblast proteome landscapes drive the
initiation and progression of cardiac fibrosis. Although the secretome of dysfunctional …

The extracellular matrix (ECM) is a highly dynamic structure controlling the proper
functioning of heart muscle. ECM remodeling with enhanced collagen deposition due to …

Aim Cardiac pathologies are accompanied by alterations in substrate metabolism, and
extracellular flux analysis is a standard tool to investigate metabolic disturbances, especially …

Cardiosphere-derived cells (CDCs) are currently being evaluated in clinical trials as a
potential therapeutic tool for regenerative medicine. The effectiveness of transplanted CDCs …

Being a biologist is a truly wonderful thing. For your job, you get to immerse yourself in the
natural world and discover the secrets of life on Earth. I can think of nothing better. Whether …

First Person is a series of interviews with the first authors of a selection of papers published
in Biology Open, helping early-career researchers promote themselves alongside their …

This study provides a radical feminist analysis of women entrepreneurs. Respondents are
drawn from an under-researched group: women who own companies with corporate …