Protein post-translational modification crosstalk in acute myeloid leukemia calls for action

M Hernandez-Valladares, R Wangen… - Current Medicinal …, 2019 - ingentaconnect.com
Background: Post-translational modification (PTM) crosstalk is a young research field.
However, there is now evidence of the extraordinary characterization of the different …

mUSP: a high-accuracy map of the in situ crosstalk of ubiquitylation and SUMOylation proteome predicted via the feature enhancement approach

HD Xu, RP Liang, YG Wang, JD Qiu - Briefings in Bioinformatics, 2021 - academic.oup.com
Reversible post-translational modification (PTM) orchestrates various biological processes
by changing the properties of proteins. Since many proteins are multiply modified by PTMs …

BioTrHMM: 基于迁移学习的生物医学命名实体识别算法.

高冰涛, 张阳, 刘斌 - Application Research of Computers …, 2019 - search.ebscohost.com
为了降低生物医学文本中命名实体识别对目标领域标注数据的需求, 将生物医学文本中的命名
实体识别问题转换为基于迁移学习的隐马尔可夫模型问题. 对要进行命名实体识别的目标领域 …

Ptm-x: Prediction of post-translational modification crosstalk within and across proteins

Y Li, Y Huang, T Li - … Methods for Predicting Post-Translational Modification …, 2022 - Springer
Posttranslational modifications (PTMs), which are processes of adding covalent groups in
protein amino acids after the translation, play an important role in regulating proteins' …

Intrinsic disorder and posttranslational modification: an evolutionary perspective

PM Harrison - Structure and Intrinsic Disorder in Enzymology, 2023 - Elsevier
Intrinsically disordered regions (IDRs) in proteins are enriched in posttranslational
modifications (PTMs). Such PTMs evidence regulatory cross talk and are linked to …

Prediction of post-translational modification cross-talk and mutation within proteins via imbalanced learning

L Deng, F Zhu, Y He, F Meng - Expert Systems with Applications, 2023 - Elsevier
Post-translational modification (PTM) is crucial for various cell signaling pathways and
biological processes. However, the interactions between PTMs (PTM cross-talk) or PTMs …

Systematic Analysis and Prediction of In Situ Cross Talk of O‐GlcNAcylation and Phosphorylation

H Yao, A Li, M Wang - BioMed research international, 2015 - Wiley Online Library
Reversible posttranslational modification (PTM) plays a very important role in biological
process by changing properties of proteins. As many proteins are multiply modified by PTMs …

Computing prediction and functional analysis of prokaryotic propionylation

LN Wang, SP Shi, PP Wen, ZY Zhou… - Journal of chemical …, 2017 - ACS Publications
Identification and systematic analysis of candidates for protein propionylation are crucial
steps for understanding its molecular mechanisms and biological functions. Although …

SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain

TT Chandrasekaran, M Choudalakis, A Broehm… - bioRxiv, 2024 - biorxiv.org
SETDB1 is a major H3K9 methyltransferase involved in heterochromatin formation and
silencing of repeat elements. It contains a unique Triple Tudor Domain (3TD) which …

[PDF][PDF] Структурно-функциональное многообразие протеоформ белка р53

СН Нарыжный, ОК Легина - Биомедицинская химия, 2019 - scholar.archive.org
Белок p53 является одним из самых изучаемых белков. По-видимому, такое
повышенное внимание к нему вызвано, прежде всего, его ключевой ролью в клеточных …