Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

[HTML][HTML] Radiopharmaceutical therapy in cancer: clinical advances and challenges

G Sgouros, L Bodei, MR McDevitt… - Nature reviews Drug …, 2020 - nature.com
Radiopharmaceutical therapy (RPT) is emerging as a safe and effective targeted approach
to treating many types of cancer. In RPT, radiation is systemically or locally delivered using …

[HTML][HTML] Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study

V Subbiah, RJ Kreitman, ZA Wainberg, JY Cho… - Annals of …, 2022 - Elsevier
Background Combined therapy with dabrafenib plus trametinib was approved in several
countries for treatment of BRAF V600E-mutant anaplastic thyroid cancer (ATC) based on an …

Current practice in patients with differentiated thyroid cancer

M Schlumberger, S Leboulleux - Nature Reviews Endocrinology, 2021 - nature.com
Considerable changes have occurred in the management of differentiated thyroid cancer
(DTC) during the past four decades, based on improved knowledge of the biology of DTC …

[HTML][HTML] Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma

W Pu, X Shi, P Yu, M Zhang, Z Liu, L Tan, P Han… - Nature …, 2021 - nature.com
The tumor ecosystem of papillary thyroid carcinoma (PTC) is poorly characterized. Using
single-cell RNA sequencing, we profile transcriptomes of 158,577 cells from 11 patients' …

The diagnosis and management of thyroid nodules: a review

C Durante, G Grani, L Lamartina, S Filetti, SJ Mandel… - Jama, 2018 - jamanetwork.com
Importance Thyroid nodules are common, being detected in up to 65% of the general
population. This is likely due to the increased use of diagnostic imaging for purposes …

Characterizing dedifferentiation of thyroid cancer by integrated analysis

H Luo, X Xia, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu… - Science …, 2021 - science.org
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …

[HTML][HTML] Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma

FH Kong, QF Ye, XY Miao, X Liu, SQ Huang, L Xiong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …

[HTML][HTML] Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics

L Lu, JR Wang, YC Henderson, S Bai… - The Journal of …, 2023 - Am Soc Clin Investig
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …

[HTML][HTML] 2019 European Thyroid Association guidelines for the treatment and follow-up of advanced radioiodine-refractory thyroid cancer

L Fugazzola, R Elisei, D Fuhrer, B Jarzab… - European thyroid …, 2019 - etj.bioscientifica.com
The vast majority of thyroid cancers of follicular origin (TC) have a very favourable outcome,
but 5–10% of cases will develop metastatic disease. Around 60–70% of this subset, hence …