Molecular tests for colorectal cancer screening

LJW Bosch, B Carvalho, RJA Fijneman… - Clinical colorectal …, 2011 - Elsevier
Detecting and removing high-risk adenomas and early colorectal cancer (CRC) can reduce
mortality of this disease. The noninvasive fecal occult blood test (FOBT; guaiac-based or …

Cell exfoliation in the human colon: myth, reality and implications for colorectal cancer screening

A Loktionov - International journal of cancer, 2007 - Wiley Online Library
Colonocyte exfoliation in the human colon constitutes a unique mechanism of cell
population control that can undergo significant changes under different physiological and …

Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc

FH Gao, XH Hu, W Li, H Liu, YJ Zhang, ZY Guo, MH Xu… - BMC cancer, 2010 - Springer
Background Oridonin, a tetracycline diterpenoid compound, has the potential antitumor
activities. Here, we evaluate the antitumor activity and action mechanisms of oridonin in …

BRDT is a novel regulator of eIF4EBP1 in renal cell carcinoma

P Wan, Z Chen, W Zhong, H Jiang… - Oncology …, 2020 - spandidos-publications.com
Among all types of kidney diseases, renal cell carcinoma (RCC) has the highest mortality,
recurrence and metastasis rates, which results in high numbers of tumor‑associated …

[HTML][HTML] Nutritional “omics” technologies for elucidating the role (s) of bioactive food components in colon cancer prevention

CD Davis, NG Hord - The Journal of nutrition, 2005 - Elsevier
Evidence continues to implicate dietary components and genetic susceptibilities as
important determinants of cancer risk and tumor behavior. Variation in cancer incidence …

The role of electrophoresis in disease biomarker discovery

HJ Issaq, TD Veenstra - Electrophoresis, 2007 - Wiley Online Library
There has been increased activity in the last few years in the search for disease markers
using fractionation of complex biological fluids combined with MS. While electrophoretic and …

Faecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer

CJ Huang, CC Chien, SH Yang… - Journal of cellular …, 2008 - Wiley Online Library
Ribosomal proteins are encoded by a gene family, members of which are overexpressed in
human cancers. Many of them have been found, using oligonucleotide microarray …

[HTML][HTML] Exfoliated colonic epithelial cells: surrogate targets for evaluation of bioactive food components in cancer prevention

A Kamra, G Kessie, JH Chen, S Kalavapudi… - The Journal of …, 2005 - Elsevier
There is significant evidence supporting the hypotheses that lifestyle, diet, and bioactive
components in foods are important modifiers of cancer risk. However, our ability to assess …

Fecal molecular markers for colorectal cancer screening

R Kanthan, JL Senger… - … research and practice, 2012 - Wiley Online Library
Despite multiple screening techniques, including colonoscopy, flexible sigmoidoscopy,
radiological imaging, and fecal occult blood testing, colorectal cancer remains a leading …

Coprocytobiology: A technical review of cytological colorectal cancer screening in fecal samples

L Ryan, YT Wong, KM Dwyer, D Clarke… - SLAS …, 2021 - journals.sagepub.com
This review discusses the field of coprocytobiology, defined as a combined method of cell
preservation, isolation, and cytology, which has applications to the investigation of …