Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

In the past few decades, the prevalence of allergic diseases has increased worldwide. Here,
we review the etiology and pathophysiology of allergic diseases, including the role of the …

Background Observational studies have suggested the association between atopic
dermatitis (AD) and the risks of autoimmune diseases. It is still unclear, however, whether or …

The prevalence of allergic rhinitis (AR) has increased tremendously in the recent year in
China. Evidence‐based medicine to objectively evaluate the prevalence and risk factors for …

The inflammation of allergic diseases is characterized by a complex interaction between
type 2 and type 3 immune responses, explaining clinical symptoms and histopathological …

Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …

The concept of “one-airway-one-disease”, coined over 20 years ago, may be an over-
simplification of the links between allergic diseases. Genomic studies suggest that rhinitis …

Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …

To investigate the association of long-term exposure to ambient air pollution with the risk of
allergic rhinitis (AR), we performed a longitudinal analysis of 379,488 participants (47.4 …

Introduction Despite well-defined clinical phenotypes of chronic rhinitis, the underlying in-
depth pathophysiological mechanism, particularly with reference to the involvement of …