Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …

Acute myeloid leukemia (AML) is a heterogeneous disease with a genetic, epigenetic, and
transcriptional etiology mainly presenting somatic and germline abnormalities. AML …

Background Immune exhaustion and senescence are dominant dysfunctional states of
effector T cells and major hurdles for the success of cancer immunotherapy. In the current …

New methods like panel-based RNA fusion sequencing (RNA-FS) promise improved
diagnostics in various malignancies. We here analyzed the impact of RNA-FS on the initial …

Acute myeloid leukemia (AML), the most common type of leukemia in older adults, is a
heterogeneous disease that originates from the clonal expansion of undifferentiated …

Background. Acute myeloid leukemia (AML) is one of the most common hematological
malignancies and accounts for about 20% of childhood leukemias. Currently …

Autologous stem cell transplantation (auto-HSCT) is a part of the therapeutic strategy for
various oncohematological diseases. The auto-HSCT procedure enables hematological …

Background Gemtuzumab ozogamicin (GO), one of the first targeted drugs used in oncology,
consists of an anti-cluster of differentiation 33 (CD33) monoclonal antibody bound to a …

Carbosilane ruthenium (II) dendrimers have been complexed with conventional anti-cancer
drugs. Due to its features, the presence of ruthenium within a dendrimer structure improves …

Acute myeloid leukemia (AML) is a hematological malignancy that commonly occurs in
children. The prognosis of pediatric AML is relatively poor, thus threatening the patient's …