Purpose Outcome of childhood acute lymphoblastic leukemia (ALL) improved greatly by
intensifying chemotherapy for all patients. Minimal residual disease (MRD) levels during the …

Although infection is the major cause of treatment-related mortality (TRM) in childhood acute
lymphoblastic leukemia, factors associated with infection-related mortality (IRM) are poorly …

Background Infections are common and are a major cause of morbidity and mortality during
treatment of childhood leukemia. We evaluated the cost effectiveness of levofloxacin …

Background The use of fluoroquinolones to prevent infections in neutropenic patients with
cancer or undergoing hematopoietic stem cell transplantation (HSCT) is a controversial …

In this study, the long-term outcome of 1818 patients treated in five consecutive clinical trials
(the cooperative study group for childhood acute lymphoblastic leukaemia (COALL) 82, 85 …

Purpose Although nonpharmacologic anti-infective measures are widely used in children
treated for acute myeloid leukemia (AML), there is little evidence of their effectiveness …

Hyperglycemia adversely affects outcome in adult patients with acute lymphoblastic
leukemia (ALL), but its impact on children with this disease is unknown. We evaluated the …

Chimeric antigen receptor T cells (CAR-Ts) constitute a novel therapeutic strategy for
relapsed/refractory B-cell malignancies. With the extensive application of CAR-T therapy in …

Background The prognosis of childhood acute lymphoblastic leukemia (ALL) is optimistic
with a 5-year event-free survival (EFS) rate of 70–85%. However, the major causes of …

Background Infection is a major complication in pediatric patients with acute lymphoblastic
leukemia during chemotherapy. In this study, the infection characteristics were determined …