Human neuronal maturation comes of age: cellular mechanisms and species differences
JL Wallace, AA Pollen - Nature Reviews Neuroscience, 2024 - nature.com
The delayed and prolonged postmitotic maturation of human neurons, compared with
neurons from other species, may contribute to human-specific cognitive abilities and …
neurons from other species, may contribute to human-specific cognitive abilities and …
Comparative transcriptomics reveals human-specific cortical features
The cognitive abilities of humans are distinctive among primates, but their molecular and
cellular substrates are poorly understood. We used comparative single-nucleus …
cellular substrates are poorly understood. We used comparative single-nucleus …
[HTML][HTML] SIMS: A deep-learning label transfer tool for single-cell RNA sequencing analysis
J Gonzalez-Ferrer, J Lehrer, A O'Farrell, B Paten… - Cell Genomics, 2024 - cell.com
Cell atlases serve as vital references for automating cell labeling in new samples, yet
existing classification algorithms struggle with accuracy. Here we introduce SIMS (scalable …
existing classification algorithms struggle with accuracy. Here we introduce SIMS (scalable …
Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics
A Morin, C Chu, P Pavlidis - bioRxiv, 2024 - biorxiv.org
The proliferation of single cell transcriptomics has potentiated our ability to unveil patterns
that reflect dynamic cellular processes, rather than cell type compositional effects that …
that reflect dynamic cellular processes, rather than cell type compositional effects that …
[HTML][HTML] Unraveling Neuronal Identities Using SIMS: A Deep Learning Label Transfer Tool for Single-Cell RNA Sequencing Analysis
J Gonzalez-Ferrer, J Lehrer, A O'Farrell, B Paten… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Large single-cell RNA datasets have contributed to unprecedented biological insight. Often,
these take the form of cell atlases and serve as a reference for automating cell labeling of …
these take the form of cell atlases and serve as a reference for automating cell labeling of …
The Brain Cells That Make Us Uniquely Human
Z Abrams - IEEE pulse, 2023 - ieeexplore.ieee.org
For over a century, scientists have known that the brain contains multiple cell types, dating
back to Santiago Ramón y Cajal's earliest observations of brain tissue under a microscope …
back to Santiago Ramón y Cajal's earliest observations of brain tissue under a microscope …
[HTML][HTML] The Brain Cells That Make Us Uniquely Human January 23, 2024
Z Abrams - embs.org
The Brain Cells That Make Us Uniquely Human https://www. embs. org/pulse/wp-
content/uploads/sites/13/2024/01/1_Abrams_AdobeStock_170601825. jpg 789 444 IEEE …
content/uploads/sites/13/2024/01/1_Abrams_AdobeStock_170601825. jpg 789 444 IEEE …