Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Abiotic stresses rewire plant central metabolism to maintain metabolic and energy
homeostasis. Metabolites involved in the plant central metabolic network serve as a hub for …

Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Key message Comprehensive metabolomic investigations provide a large set of stress-
related metabolites and metabolic pathways, advancing crops under heat stress conditions …

Progress toward the development of efficacious therapies for Alzheimer's disease (AD) is
halted by a lack of understanding early underlying pathological mechanisms. Systems …

The application of non-target analysis (NTA), a comprehensive approach to characterize
unknown chemicals, including chemicals of emerging concern has seen a steady increase …

Over the past decade, mass spectrometry (MS)-based “shotgun lipidomics” has emerged as
a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological …

Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

A new strategy has been developed for characterization of the most challenging complex
mixtures to date, using a combination of custom-designed experiments and a new data pre …