The neuroanatomy and physiology of pain can be discussed with regard to every level of the
nervous system, from peripheral nerve to cerebral cortex. Rudimentary nociception is the …

Xi'an Jiaotong University, China Acupuncture is an effective alternative therapy for pain
management. Evidence suggests that acupuncture relieves pain by exciting somatic afferent …

Les informations nociceptives en provenance de la périphérie sont traitées dans la corne
dorsale de la moelle épinière, puis elles sont projetées aux centres supra-spinaux où la …

In the central nervous system, hyperpolarization-activated, cyclic nucleotide-gated (HCN1–
4) channels have been implicated in neuronal excitability and synaptic transmission. It has …

Prior “conditioning” nerve lesions can prime DRG neurons for enhanced axon regeneration.
We tested the hypothesis that adult DRG neurons can be similarly primed for axon …

The establishment of the electrophysiological brainstem stimulation protocol allowed the
investigation of the adrenergic descending influence of the Locus coeruleus (LC) on wide …

Nucleotide-activated P2X channels and P2Y metabotropic receptors participate in
nociceptive signaling. Agonist availability is regulated by nucleoside triphosphate …

The unpleasant sensation of pain is an experience that almost all of us have already
encountered. Pain can be superficial or deep, pricking, burning, lancinating or dull, but it is …

Electronic von Frey anesthesiometry (VFA) has been previously reported by our laboratory
and others as a useful method of mechanical quantitative sensory testing (QST) for …

The brain can endogenously and powerfully modulate the processing of somatosensory
information in the spinal cord. In adults, the rostroventral medulla (RVM) can inhibit and …