Skin aging is a natural process influenced by intrinsic and extrinsic factors, and many skin
anti-aging strategies have been developed. Plants from the genus Potentilla has been used …

The skin is a critical barrier that protects against damage and infection. Within the epidermis
and dermis reside γδ T cells that play a variety of key roles in wound healing and tissue …

The skin represents the first line of defense and innate immune protection against
pathogens. Skin normally provides a physical barrier to prevent infection by pathogens; …

The well-orchestrated process of wound healing may be negatively impacted from
interrupted or incomplete tissue regenerative processes. The healing potential is further …

Background The incidence of frailty and non-healing wounds increases with patients' age.
Knowledge of the relationship between frailty and wound healing progress is greatly lacking …

Background Periploca forrestii (PF) is mainly utilized for treatment of arthritis and traumatic
injury historically. We had previously demonstrated that a fraction rich in cardiotonic steroids …

Immunotherapy has become a key new pillar of cancer treatment, and this has sparked
interest in understanding mechanisms of cancer immune evasion. It has long been …

Metabolites control immune cell functions, and delivery of these metabolites in a sustained
manner may be able to modulate function of the immune cells. In this study, alpha …

Regressive changes in epithelial stem cells underlie mammalian skin aging, but the driving
mechanisms are not well understood. Here, we report that mouse skin hair follicle stem cell …

Aging in the epidermis is marked by a gradual decline in barrier function, impaired wound
healing, hair loss, and an increased risk of cancer. This could be due to age‐related …