The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

[HTML][HTML] Gut microbiota interact with the brain through systemic chronic inflammation: implications on neuroinflammation, neurodegeneration, and aging

Y Mou, Y Du, L Zhou, J Yue, X Hu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

[HTML][HTML] Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

X Zhou, R Baumann, X Gao, M Mendoza, S Singh… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

[HTML][HTML] Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity

CH Kim - Cellular & molecular immunology, 2023 - nature.com
Immune tolerance deletes or suppresses autoreactive lymphocytes and is established at
multiple levels during the development, activation and effector phases of T and B cells …

The role of the gut microbiota in multiple sclerosis

J Correale, R Hohlfeld, SE Baranzini - Nature Reviews Neurology, 2022 - nature.com
During the past decade, research has revealed that the vast community of micro-organisms
that inhabit the gut—known as the gut microbiota—is intricately linked to human health and …

Gut microbiome in progressive multiple sclerosis

LM Cox, AH Maghzi, S Liu, SK Tankou… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to investigate the gut microbiome in progressive
multiple sclerosis (MS) and how it relates to clinical disease. Methods We sequenced the …

[HTML][HTML] Lactobacillus reuteri tryptophan metabolism promotes host susceptibility to CNS autoimmunity

TL Montgomery, K Eckstrom, KH Lile, S Caldwell… - Microbiome, 2022 - Springer
Background Dysregulation of gut microbiota-associated tryptophan metabolism has been
observed in patients with multiple sclerosis. However, defining direct mechanistic links …

[HTML][HTML] Alterations of host-gut microbiome interactions in multiple sclerosis

C Cantoni, Q Lin, Y Dorsett, L Ghezzi, Z Liu, Y Pan… - …, 2022 - thelancet.com
Background Multiple sclerosis (MS) has a complex genetic, immune and metabolic
pathophysiology. Recent studies implicated the gut microbiome in MS pathogenesis …

[HTML][HTML] The gut microbiome in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS)

RS König, WC Albrich, CR Kahlert, LS Bahr… - Frontiers in …, 2022 - frontiersin.org
Myalgic encephalomyelitis (ME) or Chronic Fatigue Syndrome (CFS) is a neglected,
debilitating multi-systemic disease without diagnostic marker or therapy. Despite evidence …

[HTML][HTML] The function of gut microbiota in immune-related neurological disorders: A review

P Sittipo, J Choi, S Lee, YK Lee - Journal of Neuroinflammation, 2022 - Springer
This review provides an overview of the importance of microbiota in the regulation of gut–
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …