Alzheimer's disease (AD) is the most common cause of dementia worldwide, and its
prevalence is rapidly increasing due to extended lifespans. Among the increasing number of …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease, affect millions of people worldwide …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

The degeneration and dysfunction of neurons are key features of neurodegenerative
diseases (NDs). Currently, one of the main challenges facing researchers and clinicians is …

MicroRNAs (miRNAs) are, small (roughly 19–25 nucleotides in length), conserved, non-
coding, single-stranded, and functional RNA molecules with the properties of gene …

ABSTRACT RNA-based therapeutics have entered the mainstream with seemingly limitless
possibilities to treat all categories of neurological disease. Here, common RNA-based drug …

Alzheimer's Disease (AD) is characterized by the accumulation of extracellular amyloid-β
(Aβ) as well as CNS and systemic inflammation. Microglia, the myeloid cells resident in the …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

One of the most prevalent neurodegenerative disorders is Alzheimer's disease (AD). Despite
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …