Epigallocatechin-3-gallate therapeutic potential in cancer: mechanism of action and clinical implications
Cellular signaling pathways involved in the maintenance of the equilibrium between cell
proliferation and apoptosis have emerged as rational targets that can be exploited in the …
proliferation and apoptosis have emerged as rational targets that can be exploited in the …
Green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG): a time for a new player in the treatment of respiratory diseases?
D Mokra, J Adamcakova, J Mokry - Antioxidants, 2022 - mdpi.com
(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …
Interactions between natural products and cancer treatments: Underlying mechanisms and clinical importance
WJJ Chan, J Adiwidjaja, AJ McLachlan… - Cancer chemotherapy …, 2023 - Springer
Natural products, also referred to as dietary supplements, complementary and alternative
medicines, and health or food supplements are widely used by people living with cancer …
medicines, and health or food supplements are widely used by people living with cancer …
Exploration of the molecular mechanism of tea polyphenols against pulmonary hypertension by integrative approach of network pharmacology, molecular docking …
H Yang, J Cao, JM Li, C Li, WW Zhou, JW Luo - Molecular Diversity, 2023 - Springer
Pulmonary hypertension, a common complication of chronic obstructive pulmonary disease,
is a major global health concern. Green tea is a popular beverage that is consumed all over …
is a major global health concern. Green tea is a popular beverage that is consumed all over …
Simultaneously inhibiting P-gp Efflux and drug recrystallization enhanced the oral bioavailability of nintedanib
J Wang, S Zhang, C Tan, Q Wei… - Current Pharmaceutical …, 2023 - ingentaconnect.com
Introduction: Nintedanib (NDNB) is a novel triple-angiokinase inhibitor for the treatment of
lung cancer. However, the oral bioavailability of NDNB is only 4.7% owing to the poor …
lung cancer. However, the oral bioavailability of NDNB is only 4.7% owing to the poor …
Tea consumption and risk of lung diseases: a two‑sample Mendelian randomization study
L Chen, Y Deng, T Wang, X Lin, L Zheng… - BMC Pulmonary …, 2023 - Springer
Background Numerous studies have reported the association between tea intake and lung
diseases. However, the probable relationship between tea consumption on lung diseases …
diseases. However, the probable relationship between tea consumption on lung diseases …
[HTML][HTML] Clinical implications of nintedanib pharmacokinetics in patients with pulmonary fibrosis
BC Agema, M Berrich, L Seuren, SDT Sassen… - Biomedicine & …, 2024 - Elsevier
Background Nintedanib is used to treat both idiopathic and progressive pulmonary fibrosis
(IPF/PPF). Evidence of both an exposure-response relationship and an exposure-toxicity …
(IPF/PPF). Evidence of both an exposure-response relationship and an exposure-toxicity …
Peimine Alleviated Bleomycin-Induced Pulmonary Fibrosis in Mice Through Reducing Epithelial-Mesenchymal Transition, Inflammation and Oxidative Stress and …
X Li, F Zhang, A Shen, J Hu… - Natural Product …, 2023 - journals.sagepub.com
Objectives Peimine (PM), derived from Fritillaria thunbergii Miq, has been demonstrated with
protective effects on pulmonary fibrosis (PF). However, the detailed mechanisms of PM on …
protective effects on pulmonary fibrosis (PF). However, the detailed mechanisms of PM on …
The Potent Potential of Green Tea In against Cardiac Disorders: A Comprehensive Review of Recent Discoveries
A preventive effect for tea and its bio active components in cardiovascular health has been
suggested by the results of several epidemiological studies, treatments utilizing randomized …
suggested by the results of several epidemiological studies, treatments utilizing randomized …