BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

Compared to most mammals, human pregnancy is unusual in that it involves chromosomally
diverse embryos, cyclical breakdown and regeneration of the uterine mucosa, and intimate …

STUDY QUESTION Can preimplantation genetic testing for aneuploidy (PGT-A) improve the
live birth rate and reduce the miscarriage rate in patients with recurrent pregnancy loss …

Less than half of human zygotes survive to birth, primarily due to aneuploidies of meiotic or
mitotic origin. Mitotic errors generate chromosomal mosaicism, defined by multiple cell …

SUMMARY ANSWER: The present ESHRE document provides 11 recommendations on
how to introduce TLT in the IVF laboratory. WHAT IS KNOWN ALREADY: Studies have been …

Background For the association between time-lapse technology (TLT) and embryo ploidy
status, there has not yet been fully understood. TLT has the characteristics of large amount …

Background In in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection
(ICSI), selection of the most competent embryo (s) for transfer is based on morphological …

In the early years of in vitro fertilization, overall pregnancy rates were low, and it was
considered necessary to transfer more than one embryo to increase the chances of …

In vitro fertilisation (IVF) is estimated to account for the birth of more than nine million babies
worldwide, perhaps making it one of the most intriguing as well as commoditised and …

Background The high incidence of aneuploidy in early human development, arising either
from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss …