Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

Microfluidic strategies for the isolation and profiling of exosomes

J Bai, X Wei, X Zhang, C Wu, Z Wang, M Chen… - TrAC Trends in …, 2023 - Elsevier
Exosomes are nanoscale extracellular vesicles carrying various cargos, which play a
significant rule in intercellular communication, disease diagnosis and treatment …

[HTML][HTML] Principles and problems of exosome isolation from biological fluids

EI Yakubovich, AG Polischouk… - … ), Supplement Series A …, 2022 - Springer
Exosomes, the subclass of small membrane extracellular vesicles, have great diagnostic
and therapeutic potential, but the lack of standardized methods for their efficient isolation …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Direct isolation of small extracellular vesicles from human blood using viscoelastic microfluidics

Y Meng, Y Zhang, M Bühler, S Wang, M Asghari… - Science …, 2023 - science.org
Small extracellular vesicles (sEVs;< 200 nm) that contain lipids, nucleic acids, and proteins
are considered promising biomarkers for a wide variety of diseases. Conventional methods …

Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models

L Qiu, Y Cai, Y Geng, X Yao, L Wang, H Cao, X Zhang… - Acta Biomaterialia, 2022 - Elsevier
Intracerebral hemorrhage following blood–brain barrier (BBB) disruption resulting from
thrombolysis of ischemic stroke with tissue plasminogen activator (tPA) remains a critical …

[HTML][HTML] Minimally invasive approaches for the early detection of endometrial cancer

Y Shen, W Yang, J Liu, Y Zhang - Molecular cancer, 2023 - Springer
Endometrial cancer (EC) is one of the most common gynecologic cancers and its incidence
is rising globally. Although advanced EC has a poor prognosis; diagnosing EC at an earlier …

[HTML][HTML] Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

[HTML][HTML] Overcoming the blood-brain barrier: Exosomes as theranostic nanocarriers for precision neuroimaging

C Li, S Qin, Y Wen, W Zhao, Y Huang, J Liu - Journal of Controlled Release, 2022 - Elsevier
Exosomes are cell-derived vesicles with a lipid bilayer membrane that play important roles
in intercellular communication. They provide an unprecedented opportunity for the …