Enteric glial biology, intercellular signalling and roles in gastrointestinal disease

L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

Enteric GFAP expression and phosphorylation in Parkinson's disease

T Clairembault, W Kamphuis… - Journal of …, 2014 - Wiley Online Library
Enteric glial cells (EGC s) are in many respects similar to astrocytes of the central nervous
system and express similar proteins including glial fibrillary acidic protein (GFAP). Changes …

Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation

G Esposito, E Capoccia, F Turco, I Palumbo, J Lu… - Gut, 2014 - gut.bmj.com
Objective Enteric glia activation has been reported to amplify intestinal inflammation via the
enteroglial-specific S100B protein. This neurotrophin promotes macrophage recruitment in …

[HTML][HTML] Protective role of berberine on ulcerative colitis through modulating enteric glial cells–intestinal epithelial cells–immune cells interactions

H Li, C Fan, H Lu, C Feng, P He, X Yang… - … Pharmaceutica Sinica B, 2020 - Elsevier
Ulcerative colitis (UC) manifests as an etiologically complicated and relapsing
gastrointestinal disease. The enteric nervous system (ENS) plays a pivotal role in rectifying …

Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione

TC Savidge, P Newman, C Pothoulakis, A Ruhl… - Gastroenterology, 2007 - Elsevier
Background & Aims: Barrier functions across epithelia and endothelia are essential for
homeostatic tissue regulation. Astroglia interact with cerebral endothelia to maintain the …

Detection and Verification of Mycobacterium avium subsp. paratuberculosis in Fresh Ileocolonic Mucosal Biopsy Specimens from Individuals with and without …

TJ Bull, EJ McMinn, K Sidi-Boumedine… - Journal of clinical …, 2003 - Am Soc Microbiol
Mycobacterium avium subsp. paratuberculosis is a robust and phenotypically versatile
pathogen which causes chronic inflammation of the intestine in many species, including …

Fundamentals of neurogastroenterology: basic science

D Grundy, ED Al–Chaer, Q Aziz, SM Collins, M Ke… - Gastroenterology, 2006 - Elsevier
The focus of neurogastroenterology in Rome II was the enteric nervous system (ENS). To
avoid duplication with Rome II, only advances in ENS neurobiology after Rome II are …

Innervation of the gastrointestinal tract: patterns of aging

RJ Phillips, TL Powley - Autonomic Neuroscience, 2007 - Elsevier
The gastrointestinal (GI) tract is innervated by intrinsic enteric neurons and by extrinsic
projections, including sympathetic and parasympathetic efferents as well as visceral …

Glial cells in the gut

A Rühl - Neurogastroenterology & Motility, 2005 - Wiley Online Library
The enteric nervous system is composed of both neurons and glia. Recent evidence
indicates that enteric glia–which vastly outnumber enteric neurons–are actively involved in …

[HTML][HTML] Enteric glial cells and their role in the intestinal epithelial barrier

YB Yu, YQ Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
The intestinal epithelium constitutes a physical and functional barrier between the external
environment and the host organism. It is formed by a continuous monolayer of intestinal …