[HTML][HTML] Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …
Molecular mechanism of VEGF and its role in pathological angiogenesis
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …
Vascular endothelial growth factor signaling in development and disease
S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …
orchestrating the development and maintenance of the blood and lymphatic vascular …
Syndecans–key regulators of cell signaling and biological functions
NA Afratis, D Nikitovic, HAB Multhaupt… - The FEBS …, 2017 - Wiley Online Library
Syndecans are a small family of four transmembrane proteoglycans in mammals. They have
similar structural organization, consisting of an N‐terminal ectodomain, single …
similar structural organization, consisting of an N‐terminal ectodomain, single …
Heparan sulfate: biosynthesis, structure, and function
JP Li, M Kusche-Gullberg - International review of cell and molecular …, 2016 - Elsevier
Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …
in the extracellular matrix of most animal tissues, having essential functions in development …
Drug therapies and delivery mechanisms to treat perturbed skin wound healing
Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …
[HTML][HTML] Neuropilin functions as an essential cell surface receptor
HF Guo, CW Vander Kooi - Journal of Biological Chemistry, 2015 - ASBMB
The Neuropilins (Nrps) are a family of essential cell surface receptors involved in multiple
fundamental cellular signaling cascades. Nrp family members have key functions in VEGF …
fundamental cellular signaling cascades. Nrp family members have key functions in VEGF …
Recent progress on cellulose‐based ionic compounds for biomaterials
Glycans play important roles in all major kingdoms of organisms, such as archea, bacteria,
fungi, plants, and animals. Cellulose, the most abundant polysaccharide on the Earth, plays …
fungi, plants, and animals. Cellulose, the most abundant polysaccharide on the Earth, plays …
The role of endothelial surface glycocalyx in mechanosensing and transduction
The endothelial cells (ECs) forming the inner wall of every blood vessel are constantly
exposed to the mechanical forces generated by blood flow. The EC responses to these …
exposed to the mechanical forces generated by blood flow. The EC responses to these …
A widespread viral entry mechanism: The C-end Rule motif–neuropilin receptor interaction
G Balistreri, Y Yamauchi… - Proceedings of the …, 2021 - National Acad Sciences
Many phylogenetically distant animal viruses, including the new coronavirus severe acute
respiratory syndrome coronavirus 2, have surface proteins with polybasic sites that are …
respiratory syndrome coronavirus 2, have surface proteins with polybasic sites that are …