[HTML][HTML] Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2

CJ Peach, VW Mignone, MA Arruda… - International journal of …, 2018 - mdpi.com
Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

Molecular mechanism of VEGF and its role in pathological angiogenesis

A Ahmad, MI Nawaz - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Over the last seven decades, a significant scientific contribution took place in the delineation
of the implications of vascular endothelial‐derived growth factor (VEGF) in the processes of …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

Syndecans–key regulators of cell signaling and biological functions

NA Afratis, D Nikitovic, HAB Multhaupt… - The FEBS …, 2017 - Wiley Online Library
Syndecans are a small family of four transmembrane proteoglycans in mammals. They have
similar structural organization, consisting of an N‐terminal ectodomain, single …

Heparan sulfate: biosynthesis, structure, and function

JP Li, M Kusche-Gullberg - International review of cell and molecular …, 2016 - Elsevier
Heparan sulfate (HS) proteoglycans (PGs) are ubiquitously expressed on cell surfaces and
in the extracellular matrix of most animal tissues, having essential functions in development …

Drug therapies and delivery mechanisms to treat perturbed skin wound healing

JS Chin, L Madden, SY Chew, DL Becker - Advanced Drug Delivery …, 2019 - Elsevier
Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …

[HTML][HTML] Neuropilin functions as an essential cell surface receptor

HF Guo, CW Vander Kooi - Journal of Biological Chemistry, 2015 - ASBMB
The Neuropilins (Nrps) are a family of essential cell surface receptors involved in multiple
fundamental cellular signaling cascades. Nrp family members have key functions in VEGF …

Recent progress on cellulose‐based ionic compounds for biomaterials

Y Yang, YT Lu, K Zeng, T Heinze, T Groth… - Advanced …, 2021 - Wiley Online Library
Glycans play important roles in all major kingdoms of organisms, such as archea, bacteria,
fungi, plants, and animals. Cellulose, the most abundant polysaccharide on the Earth, plays …

The role of endothelial surface glycocalyx in mechanosensing and transduction

Y Zeng, XF Zhang, BM Fu, JM Tarbell - Molecular, cellular, and tissue …, 2018 - Springer
The endothelial cells (ECs) forming the inner wall of every blood vessel are constantly
exposed to the mechanical forces generated by blood flow. The EC responses to these …

A widespread viral entry mechanism: The C-end Rule motif–neuropilin receptor interaction

G Balistreri, Y Yamauchi… - Proceedings of the …, 2021 - National Acad Sciences
Many phylogenetically distant animal viruses, including the new coronavirus severe acute
respiratory syndrome coronavirus 2, have surface proteins with polybasic sites that are …