Chronic noncommunicable diseases (CNCDs), which include cardiovascular disease, some
cancers, for example, colon cancer, breast cancer, and type 2 diabetes, are reaching …

Plant‐based dietary interventions have been proposed to reduce obesity induced chronic
low‐grade inflammation and hence prevent chronic disease risk; however, human evidence …

Leptin is an adipocyte-derived hormone and cytokine that regulates energy balance through
a wide range of functions, including several that are important to cardiovascular health …

Metabolic syndrome (MetS) is a collection of pathological conditions associated with
metabolic, pro-inflammatory, and prothrombotic states. MetS plays an essential role in the …

SIRT1 is a NAD+-dependent class III histone deacetylase (HDAC) that mediates the effects
of caloric restriction on lifespan and metabolic pathways in various organisms. It …

A growing body of evidence has consistently shown a correlation between obesity and
chronic subclinical inflammation. It is unclear whether the size of specific adipose depots is …

Objectives: We evaluated the hypothesis that plasma levels of adiponectin and leptin are
independently but oppositely associated with coronary artery calcification (CAC), a measure …

A obesidade vem se tornando uma epidemia global. Cerca de 1, 1 bilhões de adultos e
10% das crianças do mundo são atualmente considerados portadores de sobrepeso ou …

Strong evidence suggests that neutrophils may play an active role in acute and chronic
inflammatory disorders, such as rheumatoid arthritis and atherosclerosis. Given the role of …

Aims The mammalian silent information regulator-two 1 (Sirt1) blunts the noxious effects of
cardiovascular risk factors such as type 2 diabetes mellitus and obesity. Nevertheless, the …