Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

Until now, strategies used to treat cancer are imperfect, and this generates the need to
search for better and safer solutions. The biggest issue is the lack of selective interaction …

Abstract Cisplatin or (SP-4-2)-diamminedichloridoplatinum (II) is one of the most potential
and widely used drugs for the treatment of various solid cancers such as testicular, ovarian …

In the arena of material sciences, one of the burning topics for research has been
biogenically synthesizing nanoparticles (NPs) from plant derivatives and studying their …

The development of nanoparticle-based drug formulations has yielded the opportunities to
address and treat challenging diseases. Nanoparticles vary in size but are generally ranging …

Summary Protein homeostasis, or" proteostasis," is indispensable for a balanced, healthy
environment within the cell. However, when natural proteostasis mechanisms are …

Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer
and are responsible for imparting differential drug responses in cancer patients. Recently …

Nanotechnology is an emerging technology that deals with nanosized particles possessing
crucial research roles and application. Disciplines like chemistry, biology, physics …

Aneuploidy is a ubiquitous feature of human tumors, but the acquisition of aneuploidy
typically antagonizes cellular fitness. To investigate how aneuploidy could contribute to …

The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas) systems are efficient and versatile gene editing tools, which offer …