Unraveling the tumor microenvironment: insights into cancer metastasis and therapeutic strategies

M El-Tanani, SA Rabbani, R Babiker, I Rangraze… - Cancer Letters, 2024 - Elsevier
This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

Semiconducting polymer nanomanipulators for thermal sensitization and metastasis-inhibited synergistic cancer therapy

M Wu, R Qu, H Li, L Chen, X Zhang, Y Yuan, W Chen… - Nano Today, 2023 - Elsevier
Manipulation of intracellular protein expression is a promising cancer therapeutic approach;
however, traditional strategies relying on nonspecific molecular drugs often suffer from …

Strategies to mitigate the on-and off-target toxicities of recombinant immunotoxins: an antibody engineering perspective

M Li, S Mei, Y Yang, Y Shen, L Chen - Antibody therapeutics, 2022 - academic.oup.com
Targeted cancer therapies using immunotoxins have achieved remarkable efficacy in
hematological malignancies. However, the clinical development of immunotoxins is also …

Use of cyclodextrins in anticancer photodynamic therapy treatment

A Ben Mihoub, L Larue, A Moussaron, Z Youssef… - Molecules, 2018 - mdpi.com
Photodynamic therapy (PDT) is mainly used to destroy cancerous cells; it combines the
action of three components: a photoactivatable molecule or photosensitizer (PS), the light of …

Photothermal Therapy of Neuroblastoma via Polysialic Acid‐Targeting Nanomissiles

S Xu, M Zhao, Z Gu, H Lu, Z Liu - Small, 2022 - Wiley Online Library
Exploring new targets and developing novel targeted therapies are urgently needed for
neuroblastoma therapy. Polysialic acid (polySia), a linear homopolymer of sialic acid units …

Current stimuli-responsive mesoporous silica nanoparticles for cancer therapy

T Moodley, M Singh - Pharmaceutics, 2021 - mdpi.com
With increasing incidence and mortality rates, cancer remains one of the most devastating
global non-communicable diseases. Restricted dosages and decreased bioavailability …

[HTML][HTML] Cancer-associated fibroblasts promote the chemo-resistance in gastric cancer through secreting IL-11 targeting JAK/STAT3/Bcl2 pathway

J Ma, X Song, X Xu, Y Mou - Cancer Research and …, 2019 - synapse.koreamed.org
Purpose Our aim was to detect the potential role of interleukin 11 (IL-11) in the development
of chemo-resistance in gastric cancer and to reveal the mechanism involved in the process …

Recent developments in selenium-containing polymeric micelles: prospective stimuli, drug-release behaviors, and intrinsic anticancer activity

YS Birhan, HC Tsai - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Selenium is capable of forming a dynamic covalent bond with itself and other elements and
can undergo metathesis and regeneration reactions under optimum conditions. Its dynamic …

Colorectal cancer stem cells: A review of targeted drug delivery by gold nanoparticles

MH Mohd-Zahid, R Mohamud, CAC Abdullah, JK Lim… - RSC Advances, 2020 - pubs.rsc.org
Colorectal cancer (CRC) is one of the most common cancers with equal probability of
affecting both men and women worldwide. Recently, the newly emerged theory of cancer …

The combinatory effects of natural products and chemotherapy drugs and their mechanisms in breast cancer treatment

Y Zhang, H Li, J Zhang, C Zhao, S Lu, J Qiao… - Phytochemistry …, 2020 - Springer
Breast cancer is the leading cause of cancer-related death among females. The global
morbidity and mortality associated with breast cancer have recently been increasing …