MicroRNAs (miRNAs) contribute to the progressive changes in gene expression that occur
during development. The combined loss of all miRNAs results in embryonic lethality in all …

N6-methyladenosine (m6A) represents one of the most common RNA modifications in
eukaryotes. Specific m6A writer, eraser, and reader proteins have been identified. As an …

RNA passed from parents to progeny controls several aspects of early development. The
germline of the free-living nematode Caenorhabditis elegans contains many families of …

Translation of maternal mRNAs is detected before transcription of zygotic genes and is
essential for mammalian embryo development. How certain maternal mRNAs are selected …

Animal germ cells possess a specific post-transcriptional regulatory context allowing the
storage of maternal transcripts in the oocyte until their translation at a specific point in early …

Derepression of chromatin-mediated transcriptional repression of paternal and maternal
genomes is considered the first major step that initiates zygotic gene expression after …

Diatoms are the dominant component of the marine phytoplankton. Several diatoms produce
secondary metabolites, namely oxylipins, with teratogenic effects on their main predators …

In zebrafish, ovulated oocytes contain both maternal cortisol and the mRNA for the
glucocorticoid receptor (gr), which is spread as granular structures throughout the ooplasm …

The maternal-to-zygotic transition (MZT) is a universal step in animal development
characterized by two major events: activation of zygotic transcription and degradation of …

In response to stressful conditions, eukaryotic cells launch an arsenal of regulatory
programs to protect the proteome. One major protective response involves the arrest of …