The gut microbiota at the intersection of diet and human health

CL Gentile, TL Weir - Science, 2018 - science.org
Diet affects multiple facets of human health and is inextricably linked to chronic metabolic
conditions such as obesity, type 2 diabetes, and cardiovascular disease. Dietary nutrients …

Sarcopenic obesity: time to meet the challenge

R Barazzoni, S Bischoff, Y Boirie, L Busetto… - Obesity facts, 2018 - karger.com
The prevalence of overweight and obesity has reached epidemic proportions worldwide due
to increasingly pervasive obesogenic lifestyle changes. Obesity poses unprecedented …

[HTML][HTML] Obesity, metabolic syndrome, and musculoskeletal disease: common inflammatory pathways suggest a central role for loss of muscle integrity

KH Collins, W Herzog, GZ MacDonald… - Frontiers in …, 2018 - frontiersin.org
Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

Gut microbiota contribute to age-related changes in skeletal muscle size, composition, and function: biological basis for a gut-muscle axis

GJ Grosicki, RA Fielding, MS Lustgarten - Calcified tissue international, 2018 - Springer
Skeletal muscle is a highly plastic tissue that plays a central role in human health and
disease. Aging is associated with a decrease in muscle mass and function (sarcopenia) that …

[HTML][HTML] Alterations in intestinal microbiota diversity, composition, and function in patients with sarcopenia

L Kang, P Li, D Wang, T Wang, D Hao, X Qu - Scientific reports, 2021 - nature.com
Abstract 16S rRNA sequencing of human fecal samples has been tremendously successful
in identifying microbiome changes associated with both aging and disease. A number of …

[HTML][HTML] Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …

Interplay between food and gut microbiota in health and disease

NB Danneskiold-Samsøe, HDFQ Barros… - Food research …, 2019 - Elsevier
Numerous microorganisms colonize the human gastrointestinal tract playing pivotal roles in
relation to digestion and absorption of dietary components. They biotransform food …

[HTML][HTML] Role of gut microbiota in neuroendocrine regulation of carbohydrate and lipid metabolism via the microbiota-gut-brain-liver axis

SZ Wang, YJ Yu, K Adeli - Microorganisms, 2020 - mdpi.com
Gut microbiota play an important role in maintaining intestinal health and are involved in the
metabolism of carbohydrates, lipids, and amino acids. Recent studies have shown that the …

Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults

RA Fielding, AR Reeves, R Jasuja, C Liu… - Experimental …, 2019 - Elsevier
Evidence in support of a gut-muscle axis has been reported in rodents, but studies in older
adult humans are limited. Accordingly, the primary goals of the present study were to …

[HTML][HTML] Gut microbiota and meat quality

B Chen, D Li, D Leng, H Kui, X Bai… - Frontiers in Microbiology, 2022 - frontiersin.org
Sustainable meat production is important to providing safe and quality protein sources for
humans worldwide. Intensive artificial selection and high energy input into the diet of many …