Stress may influence the sensitivity of subjects to rewarding stimuli and stress modality may
differentially affect this sensitivity. This relation was investigated in our animal model using …

Background Stress-induced mental illnesses (mediated by neuroinflammation) pose one of
the world's most urgent public health challenges. A reliable in vivo chemical biomarker of …

The present study was designed to assess the utility of sucrose intake and intracranial self-
stimulation (ICSS) as hedonic measures for chronic mild stress (CMS) induced behavioural …

Ghrelin is a peptide hormone released by specialized X/A cells in the stomach and activated
by acylation. Following its secretion, it binds to ghrelin receptors in the periphery to regulate …

In the present study we observed that lipopolysaccharide (LPS) administration provoked a
characteristic reduction in body weight gain, food consumption, saccharin (but not water) …

Ovarian hormones exert anti-depressive and anxiolytic actions. In this study we have
analyzed the effects of ovariectomy on the development of anxiety and depression-like …

Rats and mice are widely used to study environmental effects on psychological and
metabolic health. Study designs differ widely and are often characterized by varying (social) …

The chronic mild stress (CMS) procedure was developed in rodents to target anhedonia, the
core symptom of depressive melancholia. Stress exposure has been shown to induce a …

Anhedonia is the decreased ability to experience pleasure from rewarding or enjoyable
activities, a core symptom of depression. The sucrose preference test (SPT), based on a two …

The chronic unpredictable mild stress (CMS) is a paradigm developed in animals to model
the relatively minor and unanticipated irritants that lead to a state of anhedonia in some …