It has been more than 25 years since HGF was discovered as a mitogen of hepatocytes.
HGF is produced by stromal cells, and stimulates epithelial cell proliferation, motility …

In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

Cirrhosis is a severe form of liver fibrosis that results in the irreversible replacement of liver
tissue with scar tissue in the liver. Environmental toxicity, infections, metabolic causes, or …

Bone marrow-derived mesenchymal stromal cells (MSCs) have been reported to be
beneficial for the treatment of liver fibrosis. Here, we investigated the use of genetically …

Vascular endothelial growth factor receptor (VEGFR) is a very important receptor tyrosine
kinase (RTK) that can induce angiogenesis, increase cell growth and metastasis, reduce …

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung
disease characterized by myofibroblast accumulation and extracellular matrix deposition …

Therapeutic peptides are conventionally administered via subcutaneous injection. Chitosan-
based nanoparticles are gaining increased attention for their ability to serve as a carrier for …

Chronic liver injury from various causes often results in liver fibrosis (LF). Although the liver
possesses endogenous tissue-repairing activities, these can be overcome by sustained …

Purpose: We tested the potential of bone morphogenic protein 7 (BMP7) and hepatocyte
growth factor (HGF) combination gene therapy to treat preformed corneal fibrosis using …

The objective of the present study was to investigate the effect of melatonin on the liver
inflammatory and regenerative response in an animal model of fulminant hepatic failure …