Neuroprotection of cannabidiol, its synthetic derivatives and combination preparations against microglia-mediated neuroinflammation in neurological disorders

M Yousaf, D Chang, Y Liu, T Liu, X Zhou - Molecules, 2022 - mdpi.com
The lack of effective treatment for neurological disorders has encouraged the search for
novel therapeutic strategies. Remarkably, neuroinflammation provoked by the activated …

Comprehensive utilization of thinned unripe fruits from horticultural crops

M Wei, H Wang, T Ma, Q Ge, Y Fang, X Sun - Foods, 2021 - mdpi.com
Fruit thinning is a cultivation technique that is widely applied in horticulture in order to obtain
high-quality horticultural crops. This practice results in the discarding of a large number of …

The protective effects of curcumin on metabolic syndrome and its components: In-silico analysis for genes, transcription factors, and microRNAs involved

HD Nguyen, MS Kim - Archives of Biochemistry and Biophysics, 2022 - Elsevier
Background We aimed to identify the molecular mechanisms behind curcumin's therapeutic
benefits for metabolic syndrome (MetS) and its components. Methods The Comparative …

[HTML][HTML] Anti-inflammatory effects and improved metabolic derangements in ob/ob mice by a newly synthesized prenylated benzopyran with pan-PPAR activity

P Marques, C Villarroel-Vicente, A Collado… - Pharmacological …, 2023 - Elsevier
Background and purpose Selective peroxisome proliferator-activated receptors (PPARs) are
widely used to treat metabolic complications; however, the limited effect of PPARα agonists …

Lactobacillus plantarum ZJUIDS14 alleviates non-alcoholic fatty liver disease in mice in association with modulation in the gut microbiota

F Cao, Q Ding, H Zhuge, S Lai, K Chang, C Le… - Frontiers in …, 2023 - frontiersin.org
This present study was designed to explore the protective role of Lactobacillus plantarum
ZJUIDS14 against Non-alcoholic Fatty Liver Disease (NAFLD) in a high-fat-diet (HFD) …

Ciabatta Bread Incorporating Goji (Lycium barbarum L.): A New Potential Functional Product with Impact on Human Health

V Sicari, R Romeo, A Mincione, S Santacaterina… - Foods, 2023 - mdpi.com
This work investigated the phytochemical content and bioactivity of Lycium barbarum
collected in Calabria and evaluated, for the first time, the possibility of enriching traditional …

Sepsis‑induced cardiac dysfunction and pathogenetic mechanisms

J Song, X Fang, K Zhou, H Bao… - Molecular Medicine …, 2023 - spandidos-publications.com
Sepsis is a manifestation of the immune and inflammatory response to infection, which may
lead to multi‑organ failure. Health care advances have improved outcomes in critical illness …

Benzopyran hydrazones with dual PPARα/γ or PPARα/δ agonism and an anti-inflammatory effect on human THP-1 macrophages

A García, L Vila, I Duplan, MA Schiel, RD Enriz… - European Journal of …, 2024 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) play a major role in regulating
inflammatory processes, and dual or pan-PPAR agonists with PPARγ partial activation have …

Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties

J Stanková, M Jurášek, M Hajdúch… - Journal of Natural …, 2024 - ACS Publications
Advancements in small-molecule research have created the need for sensitive techniques to
accurately study biological processes in living systems. Fluorescent-labeled probes have …

Transcriptome analysis provides insight into the anti-diabetic mechanism of theaflavins in high-fat diet and streptozotocin-induced mice

K Wang, J Wu, S Chen, H Zhao, P He, Y Tu, B Li - Food & Function, 2022 - pubs.rsc.org
Black tea exhibits potential to improve hyperglycemia and insulin resistance, where
theaflavins (TFs) are its characteristic components. The aim of this study was to explore the …