Health-related quality of life, palliative care needs and 12-month survival among patients with end stage renal disease in Uganda: protocol for a mixed methods …

P Bagasha, M Leng, E Katabira, M Petrova - BMC nephrology, 2020 - Springer
Background The prevalence of chronic kidney disease is on the rise globally and in sub-
Saharan Africa. Due to its “silent” nature, many patients often present with advanced …

COVID-19-related laboratory analyte changes and the relationship between SARS-CoV-2 and HIV, TB, and HbA1c in South Africa

R Hesse, DJ van der Westhuizen… - Clinical, Biological and …, 2021 - Springer
We conducted a retrospective analysis on data of all adults tested for SARS-CoV-2 across
our laboratory network in South Africa over a 4-month period. Out of 842,197 tests, 11.7 …

Methods to estimate baseline creatinine and define acute kidney injury in lean Ugandan children with severe malaria: a prospective cohort study

A Batte, MC Starr, AL Schwaderer, RO Opoka… - BMC nephrology, 2020 - Springer
Background Acute kidney injury (AKI) is increasingly recognized as a consequential clinical
complication in children with severe malaria. However, approaches to estimate baseline …

High Rates of Undiagnosed Target Organ Damage Among Adults with Elevated Blood Pressure or Diabetes Mellitus in a Community-Based Survey in Lesotho

E Firima, L Gonzalez, MA Khan… - Journal of Epidemiology …, 2023 - Springer
Introduction Prevalence of elevated blood pressure (BP) and diabetes mellitus (DM) is
increasing in sub-Saharan Africa. Data on target organ damage such as retinopathy, left …

SARS-CoV-2 infection and the kidneys: an evolving picture

JA George, S Khoza - Identification of Biomarkers, New Treatments, and …, 2021 - Springer
Since December 2019, a novel coronavirus known as Severe Acute Respiratory Virus 2
(SARS-CoV-2) has caused an outbreak of a respiratory illness worldwide. Even though …

Renal outcomes in adults with HBV, HIV and HBV/HIV coinfection after 3 years of antiviral therapy in urban Tanzania

EL Wu, B Christian, AS Rivera, E Fabian… - Journal of …, 2024 - academic.oup.com
Background An enhanced understanding of renal outcomes in persons with chronic HBV,
HIV, and HBV/HIV coinfection is needed to mitigate chronic kidney disease in regions where …

Genetic association and transferability for urinary albumin-creatinine ratio as a marker of kidney disease in four Sub-Saharan African populations and non-continental …

JT Brandenburg, WC Chen, PR Boua… - Frontiers in …, 2024 - frontiersin.org
Background Genome-wide association studies (GWAS) have predominantly focused on
populations of European and Asian ancestry, limiting our understanding of genetic factors …

Prevalence, incidence and predictors of renal impairment in persons with HIV receiving protease-inhibitors in rural Tanzania

H Mapesi, J Okuma, F Franzeck, HI Wilson, E Senkoro… - Plos one, 2021 - journals.plos.org
Objective Ritonavir-boosted protease inhibitors (bPI) in people living with HIV (PLWH) have
been associated with renal impairment. Limited data are available from rural sub-Saharan …

Expression of whole blood miR-126-3p,-30a-5p,-1299,-182-5p and-30e-3p in chronic kidney disease in a South African community-based sample

DD Motshwari, C George, DM Matshazi, CJ Weale… - Scientific Reports, 2022 - nature.com
The burden of chronic kidney disease (CKD) in Africa remains poorly characterized, due
partly to the lack of appropriate diagnostic strategies. Although in recent years the diagnostic …

Demographic and clinical profile of black patients with chronic kidney disease attending a tertiary hospital in Johannesburg, South Africa

A Meremo, G Paget, R Duarte, C Dickens, T Dix-Peek… - Plos one, 2022 - journals.plos.org
Background The prevalence of chronic kidney disease (CKD) is increasing worldwide; black
patients have an increased risk of developing CKD and end stage kidney disease (ESKD) at …