On iron metabolism and its regulation

ACS Vogt, T Arsiwala, M Mohsen, M Vogel… - International journal of …, 2021 - mdpi.com
Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Physiologically active molecules and functional properties of soybeans in human health—A current perspective

IS Kim, CH Kim, WS Yang - International journal of molecular sciences, 2021 - mdpi.com
In addition to providing nutrients, food can help prevent and treat certain diseases. In
particular, research on soy products has increased dramatically following their emergence …

Overview of Helicobacter pylori Infection: Clinical Features, Treatment, and Nutritional Aspects

M Öztekin, B Yılmaz, D Ağagündüz, R Capasso - Diseases, 2021 - mdpi.com
Helicobacter pylori (H. pylori) is a 0.5–1 µm wide, 2–4 µm long, short helical, S-shaped
Gram-negative microorganism. It is mostly found in the pyloric region of the stomach and …

Fluorogenic toolbox for facile detecting of hydroxyl radicals: From designing principles to diagnostics applications

J Wu, Y Zhao, K Li, S Muhammad, M Ju, L Liu… - TrAC Trends in …, 2022 - Elsevier
Reactive oxygen species (ROS) are a class of active substances containing oxygen, which
widely exist in biological entities and natural environment. Among them, hydroxyl radicals (• …

Melatonin: Potential avenue for treating iron overload disorders

J Yang, Q Tang, Y Zeng - Ageing Research Reviews, 2022 - Elsevier
Iron overload as a highly risk factor, can be found in almost all human chronic and common
diseases. Iron chelators are often used to treat iron overload; however, patient adherence to …

Toxic feedback loop involving iron, reactive oxygen species, α-synuclein and neuromelanin in Parkinson's disease and intervention with turmeric

Z Jansen van Rensburg, S Abrahams, S Bardien… - Molecular …, 2021 - Springer
Parkinson's disease (PD) is a movement disorder associated with severe loss of mainly
dopaminergic neurons in the substantia nigra. Pathological hallmarks include Lewy bodies …

Iron and ferroptosis more than a suspect: beyond the most common mechanisms of neurodegeneration for new therapeutic approaches to cognitive decline and …

M Cerasuolo, I Di Meo, MC Auriemma, F Trojsi… - International Journal of …, 2023 - mdpi.com
Neurodegeneration is a multifactorial process that involves multiple mechanisms. Examples
of neurodegenerative diseases are Parkinson's disease, multiple sclerosis, Alzheimer's …

Age-related changes and sex-related differences in brain iron metabolism

T Grubić Kezele, B Ćurko-Cofek - Nutrients, 2020 - mdpi.com
Iron is an essential element that participates in numerous cellular processes. Any disruption
of iron homeostasis leads to either iron deficiency or iron overload, which can be detrimental …

Quantitation of Brain and Blood Glutathione and Iron in Healthy Age Groups Using Biophysical and In Vivo MR Spectroscopy: Potential Clinical Application

PK Mandal, D Dwivedi, S Joon, A Goel… - ACS Chemical …, 2023 - ACS Publications
The antioxidant glutathione (GSH) and pro-oxidant iron levels play a balancing role in the
modulation of oxidative stress (OS). There is a significant depletion of GSH in the left …

Modifiable, non-modifiable, and clinical factors associated with progression of Alzheimer's disease

DA Loeffler - Journal of Alzheimer's Disease, 2021 - content.iospress.com
There is an extensive literature relating to factors associated with the development of
Alzheimer's disease (AD), but less is known about factors which may contribute to its …