[HTML][HTML] Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition
X Li, X Jiang, H Chu, Q Zhao, H Ding, C Cai - Chinese Herbal Medicines, 2021 - Elsevier
Objective Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in
substantia nigra (SN). Our previous study demonstrated kukoamine A (KuA) to exhibit strong …
substantia nigra (SN). Our previous study demonstrated kukoamine A (KuA) to exhibit strong …
[HTML][HTML] Nanoscale Two-Dimensional FeII- and CoII-Based Metal–Organic Frameworks of Porphyrin Ligand for the Photodynamic Therapy of Breast Cancer
Q Li, BW Xu, YM Zou, RJ Niu, JX Chen, WH Zhang… - Molecules, 2023 - mdpi.com
The delivery of biocompatible reagents into cancer cells can elicit an anticancer effect by
taking advantage of the unique characteristics of the tumor microenvironment (TME). In this …
taking advantage of the unique characteristics of the tumor microenvironment (TME). In this …
[HTML][HTML] Oxidative Stress: The Role of Estrogen and Progesterone
A Cagnacci, I Gazzo, S Stigliani, AM Paoletti… - Journal of Clinical …, 2023 - mdpi.com
The effect of estrogen and progesterone on oxidative status is not yet very clear,
improvements and detrimental effects having been reported with the use of menopausal …
improvements and detrimental effects having been reported with the use of menopausal …
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer's disease
Alzheimer's disease (AD) is the most ubiquitous neurodegenerative disorder with impaired
cognitive functionality. Till date, the specific pathophysiology related to AD is still elusive …
cognitive functionality. Till date, the specific pathophysiology related to AD is still elusive …
Efficient Electrochemical Microsensor for the Simultaneous Measurement of Hydrogen Peroxide and Ascorbic Acid in Living Brains
Q Chen, R Lin, W Wang, Y Zuo, Y Zhuo, Y Yu… - Analytical …, 2024 - ACS Publications
Hydrogen peroxide (H2O2) and ascorbic acid (AA), acting as two significant indicative
species, correlate with the oxidative stress status in living brains, which have historically …
species, correlate with the oxidative stress status in living brains, which have historically …
[HTML][HTML] Brain-derived neurotrophic factor interplay with oxidative stress: neuropathology approach in potential biomarker of Alzheimer's disease
The aging population poses a serious challenge concerning an increased prevalence of
Alzheimer's disease (AD) and its impact on global burden, morbidity, and mortality. Oxidative …
Alzheimer's disease (AD) and its impact on global burden, morbidity, and mortality. Oxidative …
Attenuation of the mutual elevation of iron accumulation and oxidative stress may contribute to the neuroprotective and anti-seizure effects of xenon in neonatal …
M Zhang, Y Cui, W Zhu, J Yu, Y Cheng, X Wu… - Free Radical Biology …, 2020 - Elsevier
Previous studies have suggested that xenon inhalation has neuroprotective and
antiepileptic effects; however, the underlying mechanisms involved remain unclear. This …
antiepileptic effects; however, the underlying mechanisms involved remain unclear. This …
[HTML][HTML] Effect of hydroxyl groups esterification with fatty acids on the cytotoxicity and antioxidant activity of flavones
G Kubiak-Tomaszewska, P Roszkowski… - Molecules, 2022 - mdpi.com
Flavonoids and polyunsaturated fatty acids due to low cytotoxicity in vitro studies are
suggested as potential substances in the prevention of diseases associated with oxidative …
suggested as potential substances in the prevention of diseases associated with oxidative …
[HTML][HTML] Bioinorganic modulators of ferroptosis: a review of recent findings
A Bartos, J Sikora - International Journal of Molecular Sciences, 2023 - mdpi.com
Ferroptosis was first reported as a separate modality of regulated cell death in 2008 and
distinguished under its current name in 2012 after it was first induced with erastin. In the …
distinguished under its current name in 2012 after it was first induced with erastin. In the …
Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative …
M Ligaj, J Kobus-Cisowska, O Szczepaniak, P Szulc… - Talanta, 2021 - Elsevier
A new way of electrochemical DNA sensor using as a screening tool for the determination of
phytochemicals with high genoprotective functionality is proposed. The biosensor's …
phytochemicals with high genoprotective functionality is proposed. The biosensor's …