[HTML][HTML] Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition

X Li, X Jiang, H Chu, Q Zhao, H Ding, C Cai - Chinese Herbal Medicines, 2021 - Elsevier
Objective Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in
substantia nigra (SN). Our previous study demonstrated kukoamine A (KuA) to exhibit strong …

[HTML][HTML] Nanoscale Two-Dimensional FeII- and CoII-Based Metal–Organic Frameworks of Porphyrin Ligand for the Photodynamic Therapy of Breast Cancer

Q Li, BW Xu, YM Zou, RJ Niu, JX Chen, WH Zhang… - Molecules, 2023 - mdpi.com
The delivery of biocompatible reagents into cancer cells can elicit an anticancer effect by
taking advantage of the unique characteristics of the tumor microenvironment (TME). In this …

[HTML][HTML] Oxidative Stress: The Role of Estrogen and Progesterone

A Cagnacci, I Gazzo, S Stigliani, AM Paoletti… - Journal of Clinical …, 2023 - mdpi.com
The effect of estrogen and progesterone on oxidative status is not yet very clear,
improvements and detrimental effects having been reported with the use of menopausal …

Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer's disease

A Dhiman, M Handa, M Ruwali, DP Singh… - Mitochondrion, 2022 - Elsevier
Alzheimer's disease (AD) is the most ubiquitous neurodegenerative disorder with impaired
cognitive functionality. Till date, the specific pathophysiology related to AD is still elusive …

Efficient Electrochemical Microsensor for the Simultaneous Measurement of Hydrogen Peroxide and Ascorbic Acid in Living Brains

Q Chen, R Lin, W Wang, Y Zuo, Y Zhuo, Y Yu… - Analytical …, 2024 - ACS Publications
Hydrogen peroxide (H2O2) and ascorbic acid (AA), acting as two significant indicative
species, correlate with the oxidative stress status in living brains, which have historically …

[HTML][HTML] Brain-derived neurotrophic factor interplay with oxidative stress: neuropathology approach in potential biomarker of Alzheimer's disease

R Shen, C Ardianto, C Celia, VM Sidharta… - Dementia & …, 2023 - SciELO Brasil
The aging population poses a serious challenge concerning an increased prevalence of
Alzheimer's disease (AD) and its impact on global burden, morbidity, and mortality. Oxidative …

Attenuation of the mutual elevation of iron accumulation and oxidative stress may contribute to the neuroprotective and anti-seizure effects of xenon in neonatal …

M Zhang, Y Cui, W Zhu, J Yu, Y Cheng, X Wu… - Free Radical Biology …, 2020 - Elsevier
Previous studies have suggested that xenon inhalation has neuroprotective and
antiepileptic effects; however, the underlying mechanisms involved remain unclear. This …

[HTML][HTML] Effect of hydroxyl groups esterification with fatty acids on the cytotoxicity and antioxidant activity of flavones

G Kubiak-Tomaszewska, P Roszkowski… - Molecules, 2022 - mdpi.com
Flavonoids and polyunsaturated fatty acids due to low cytotoxicity in vitro studies are
suggested as potential substances in the prevention of diseases associated with oxidative …

[HTML][HTML] Bioinorganic modulators of ferroptosis: a review of recent findings

A Bartos, J Sikora - International Journal of Molecular Sciences, 2023 - mdpi.com
Ferroptosis was first reported as a separate modality of regulated cell death in 2008 and
distinguished under its current name in 2012 after it was first induced with erastin. In the …

Electrochemical screening of genoprotective and antioxidative effectiveness of Origanum vulgare L. and its functionality in the prevention of neurodegenerative …

M Ligaj, J Kobus-Cisowska, O Szczepaniak, P Szulc… - Talanta, 2021 - Elsevier
A new way of electrochemical DNA sensor using as a screening tool for the determination of
phytochemicals with high genoprotective functionality is proposed. The biosensor's …